The. llltl'.. l inlportallt Itlnclioll o| nl; lllg, lllC~, C ill biology is to catalyze Iht conxcrsion ot water
to molecular oxygen. Thb, process t;. ikc~, place in l'tlolos~ Mem II near the lumenal surface …

Given the well-defined enzymology of the manganese catalases and recent advances in the
structural biology of these proteins, this is an excellent area for corroborative modeling of the …

The purpose of this article is twofold. First, to review the recent literature dealing with the
mechanisms of catalysis by binuclear manganese enzymes. Second, to summarize and …

Background: Catalases are important antioxidant metalloenzymes that catalyze
disproportionation of hydrogen peroxide, forming dioxygen and water. Two families of …

Manganese catalases (MnCAT) and superoxide dismutases (MnSOD) deplete hydrogen
peroxide and superoxide in cells through a ping-pong mechanism involving cyclic oxidation …

Among the first row transition metals, the element manganese is second only to iron in terms
of its te: rrestrial abundance. Manganese constitutes about 0.085% of the earth's crust, and …

Non-heme manganese catalases are widely distributed over microbial life and represent an
environmentally important alternative to heme-containing catalases in antioxidant defense …

Phosphotriesterase: an enzyme in search of its natural substrate Page 61
PHOSPHOTRIESTERASE: AN ENZYME IN SEARCH OF ITS NATURAL SUBSTRATE By FRANK …

The crystal structures of two forms of the enzyme dimanganese catalase from Thermus
Thermophilus (native and inhibited by chloride) were studied by X-ray diffraction analysis at …

Escherichia coli class Ib ribonucleotide reductase (RNR) converts nucleoside 5′-
diphosphates to deoxynucleoside 5′-diphosphates and is expressed under iron-limited …