Endometriosis is a common condition associated with infertility that causes chronic pain in
many, but not all, women. It is defined by the presence of endometrial-like tissue outside the …

BACKGROUND The endometrium is the primary target organ for the 'female'sex steroid
hormone estrogen, which exerts effects in the endometrium via two main classical estrogen …

Endometriosis occurs in approximately 10% of women and is associated with persistent
pelvic pain. It is defined by the presence of endometrial tissue (lesions) outside the uterus …

Background Human umbilical endothelial cells (HUVECs) are widely used to study the
endothelial physiology and pathology that might be involved in sex and gender differences …

Context: Identifying novel molecular markers for assessing endometrial receptivity is
necessary for understanding human implantation and may help in improving the clinical …

Normal pregnancy is associated with dramatic increases in uterine blood flow to facilitate the
bidirectional maternal–fetal exchanges of respiratory gases and to provide sole nutrient …

The endometrium is a complex multicellular tissue that is exquisitely sensitive to the actions
of sex steroids synthesised in the ovary (endocrine system). Recent studies have highlighted …

Peripheral tissue metabolism of steroids (intracrinology) is now accepted as a key way in
which tissues, such as the endometrium, can utilise inactive steroids present in the blood to …

STUDY QUESTION Does intrauterine biosynthesis of estrogen play an important role in
early pregnancy by altering the function of uterine natural killer (uNK) cells? SUMMARY …

Context: Ovarian suppression is a common treatment for endometriosis-associated pelvic
pain. Its exact mechanism of action is poorly understood, although it is assumed to reflect …