Natriuretic peptides: role in the diagnosis and management of heart failure: a scientific statement from the Heart Failure Association of the European Society of …

H Tsutsui, NM Albert, AJS Coats, SD Anker… - Journal of Cardiac …, 2023 - Elsevier
Natriuretic peptides, brain (B-type) natriuretic peptide (BNP) and N-terminal prohormone of
brain natriuretic peptide (NT-proBNP) are globally and most often used for the diagnosis of …

Neprilysin inhibitors in heart failure: the science, mechanism of action, clinical studies, and unanswered questions

B Bozkurt, AP Nair, A Misra, CZ Scott, JH Mahar… - Basic to Translational …, 2023 - jacc.org
This article provides a contemporary review and a new perspective on the role of neprilysin
inhibition in heart failure (HF) in the context of recent clinical trials and addresses potential …

Heart failure: an update from the last years and a look at the near future

M Riccardi, AM Sammartino, M Piepoli… - ESC heart …, 2022 - Wiley Online Library
In the last years, major progress occurred in heart failure (HF) management. Quadruple
therapy is now mandatory for all the patients with HF with reduced ejection fraction. Whilst …

Guideline‐directed medical therapy in severe heart failure with reduced ejection fraction: An analysis from the HELP‐HF registry

D Tomasoni, M Pagnesi, G Colombo… - European Journal of …, 2024 - Wiley Online Library
Aim Persistent symptoms despite guideline‐directed medical therapy (GDMT) and poor
tolerance of GDMT are hallmarks of patients with advanced heart failure (HF) with reduced …

Advanced heart failure: guideline‐directed medical therapy, diuretics, inotropes, and palliative care

D Tomasoni, JKK Vishram‐Nielsen… - ESC heart …, 2022 - Wiley Online Library
Heart failure (HF) is a major cause of mortality, hospitalizations, and reduced quality of life
and a major burden for the healthcare system. The number of patients that progress to an …

Inotropic therapy in patients with advanced heart failure. A clinical consensus statement from the Heart Failure Association of the European Society of Cardiology

F Gustafsson, K Damman, S Nalbantgil… - European Journal of …, 2023 - Wiley Online Library
This clinical consensus statement reviews the use of inotropic support in patients with
advanced heart failure. The current guidelines only support use of inotropes in the setting of …

Natriuretic peptide pathways in heart failure: further therapeutic possibilities

SJ Sangaralingham, M Kuhn, V Cannone… - Cardiovascular …, 2022 - academic.oup.com
The discovery of the heart as an endocrine organ resulted in a remarkable recognition of the
natriuretic peptide system (NPS). Specifically, research has established the production of …

Semaglutide and NT-proBNP in obesity-related HFpEF: insights from the STEP-HFpEF Program

MC Petrie, BA Borlaug, J Butler, MJ Davies… - Journal of the American …, 2024 - jacc.org
Background The glucagon-like peptide-1 receptor agonist, semaglutide, improved health
status and reduced body weight in patients with obesity-related heart failure (HF) with …

Consensus statement on the current pharmacological prevention and management of heart failure

AP Sindone, C De Pasquale, J Amerena… - Medical Journal of …, 2022 - Wiley Online Library
Introduction: This consensus statement of Australian clinicians provides new
recommendations for the pharmacological management of heart failure based on studies …

Soluble guanylate cyclase stimulators in patients with heart failure with reduced ejection fraction across the risk spectrum

J Butler, MS Usman, KJ Anstrom… - European Journal of …, 2022 - Wiley Online Library
Patients with heart failure with reduced ejection fraction (HFrEF) have a high residual risk of
adverse outcomes, even when treated with optimal guideline‐directed medical therapy and …