The optical microscope has revolutionized biology since at least the 17th Century. Since
then, it has progressed from a largely observational tool to a powerful bioanalytical platform …

Significance Photoacoustic (PA) imaging (PAI) represents an emerging modality within the
realm of biomedical imaging technology. It seamlessly blends the wealth of optical contrast …

We report the development of a head-mounted photoacoustic fiberscope for cerebral
imaging in a freely behaving mouse. The 4.5-gram imaging probe has a 9-µm lateral …

Micro–electro–mechanical systems (MEMS)-based optical scanners play a vital role in the
development of miniaturized optical imaging modalities. However, there is a longstanding …

Significance There are many neuroscience questions that can be answered by a high-
resolution functional brain imaging system. Such a system would require the capability to …

This study presents a miniaturized head-mount optical coherence tomography (OCT) system
tailored for high-resolution brain imaging in freely moving mice, providing an advanced …

In vivo imaging plays an important role in investigating how the glymphatic system drains
metabolic waste and pathological proteins from the central nervous system. However, the …

A miniaturized photoacoustic fiberscope has been developed, featuring a lateral resolution
of 9 microns and a lightweight design at 4.5 grams. Engineered to capture hemodynamic …

Photoacoustic imaging (PAI) is a novel modality in biomedical imaging technology that
combines the rich optical contrast with the deep penetration of ultrasound. To date, PAI …

A wideband sensitive needle ultrasound sensor based on a polarized PVDF-TrFE
copolymer piezoelectric film has been developed, which is capable of providing a noise …