The role of oxidative stress in the physiopathology of human pregnancy is of particular
interest. Pregnancy is well-known to increase the oxidative stress, mainly produced by a …

Untainted environment promotes health, but the last few decades experienced steep
upsurge in environmental contaminants posing detrimental physiological impact. The …

Placental insufficiency and adipose tissue dysregulation are postulated to play key roles in
the pathophysiology of both pre-eclampsia (PE) and gestational diabetes mellitus (GDM). A …

During the perinatal period, free radicals (FRs) are involved in several physiological roles
such as the cellular responses to noxia, the defense against infectious agents, the regulation …

Based on epidemiological observations Barker et al. put forward the hypothesis/concept that
an adverse intrauterine environment (involving an insufficient nutrient supply, chronic …

Background As a novel prognostic and inflammatory marker, the systemic immune-
inflammation index (SII) has come to the foreground in recent years. SII may be used as an …

Preeclampsia is a pregnancy-specific syndrome that has been the greatest cause of
maternal and fetal morbidity and mortality. The impaired outcomes are related to maternal …

Overweight and obesity have become a dangerous disease requiring multiple interventions,
treatment and preventions. In women of reproductive age, obesity is one of the most …

The development of lower extremity venous insufficiency (VI) during pregnancy has been
associated with placental damage. VI is associated with increased oxidative stress in …

Oxidative stress and endothelial dysfunction contribute substantially to the pathogenesis of
preeclampsia (PE). Decidual mesenchymal stem/stromal cells (DMSC), reportedly reduce …