The association between Hymenoptera venom‐triggered anaphylaxis (HVA) and clonal
mast cell‐related disorders (cMCD) has been known for decades. However, recent …

Mast cells (MCs) are stationary cells and are present in all vascularized tissues. 1–4
Although their physiologic role is thought to be supporting innate immunity, wound healing …

Background Anaphylaxis is a well-known feature of mastocytosis, particularly in relation to
hymenoptera venom stings. It is therefore hypothesized that mastocytosis patients may also …

Our knowledge of biology and mast cell (MC) function, as well as disorders associated with
the pathologic activation of MCs, has evolved over the last few decades. Anaphylaxis, mast …

Background The Red Española de Mastocitosis (Spanish Network on Mastocytosis) score
(REMAs) and the National Institutes of Health idiopathic clonal anaphylaxis score (NICAS) …

Opinion statement Mastocytosis is associated with a high risk of anaphylaxis, in part due to
drug hypersensitivity reactions (DHR). Drugs associated with mast cell activation include …

Background: Anaphylactic reactions are a well-known feature of mastocytosis, particularly in
relation to hymenoptera venom stings. Although data on the frequency of drug …

Mastocytosis is a myeloproliferative neoplasm characterized by abnormal proliferation and
activation of clonal mast cells typically bearing the KITD816V mutation. Symptoms manifest …

“Doctor, I cannot take any pain medications. I have mastocytosis.–Have you ever had a
reaction to aspirin, ibuprofen or other similar medications?–I have never tried since I was …

Background Anaphylaxis is a common feature of patients with mastocytosis, particularly with
Hymenoptera venoms. Hence, it is hypothesized that patients with mastocytosis may have …