The Hippo signaling pathway is a highly conserved pathway involved in tissue development
and regeneration that controls organ size through the regulation of cell proliferation and …

Glioblastoma, also referred to as glioblastoma multiforme (GBM), is grade IV astrocytoma
characterized by being fast-growing and the most aggressive brain tumor. In adults, it is the …

Tumor necrosis commonly exists and predicts poor prognoses in many cancers. Although it
is thought to result from chronic ischemia, the underlying nature and mechanisms driving the …

YAP1 fusion-positive supratentorial ependymomas predominantly occur in infants, but the
molecular mechanisms of oncogenesis are unknown. Here we show YAP1-MAMLD1 …

Atherosclerosis is a chronic inflammatory disease and the pathological basis of many fatal
cardiovascular diseases. Macrophages, the main inflammatory cells in atherosclerotic …

T-cell receptor stimulation triggers cytosolic Ca 2+ signaling by inositol-1, 4, 5-trisphosphate
(IP 3)-mediated Ca 2+ release from the endoplasmic reticulum (ER) and Ca 2+ entry through …

The Hippo signaling pathway is highly conserved from Drosophila melanogaster to
mammals and plays a crucial role in organ size control, tissue regeneration, and tumor …

The Hippo pathway effector TAZ promotes cellular growth, survival, and stemness through
regulating gene transcription. Recent studies suggest that TAZ liquid–liquid phase …

Cancer is a complex group of diseases that constitute the second largest cause of mortality
worldwide. The development of new drugs for treating this disease is a long and costly …

The Hippo signaling pathway is a master regulator of organ size and tissue homeostasis.
Hippo integrates a broad range of cellular signals to regulate numerous processes, such as …