Acoustic behavior of microbubbles and implications for drug delivery

K Kooiman, HJ Vos, M Versluis, N De Jong - Advanced drug delivery …, 2014 - Elsevier
Ultrasound contrast agents are valuable in diagnostic ultrasound imaging, and they
increasingly show potential for drug delivery. This review focuses on the acoustic behavior …

Ultrasound contrast imaging: Fundamentals and emerging technology

H Yusefi, B Helfield - Frontiers in Physics, 2022 - frontiersin.org
The development of microbubble contrast agents has broadened the scope of medical
ultrasound imaging. Along with dedicated imaging techniques, these agents provide …

Molecular ultrasound imaging: current status and future directions

N Deshpande, A Needles, JK Willmann - Clinical radiology, 2010 - Elsevier
Targeted contrast-enhanced ultrasound (molecular ultrasound) is an emerging imaging
strategy that combines ultrasound technology with novel molecularly-targeted ultrasound …

Targeting of microbubbles: contrast agents for ultrasound molecular imaging

S Wang, JA Hossack, AL Klibanov - Journal of drug targeting, 2018 - Taylor & Francis
For contrast ultrasound imaging, the most efficient contrast agents comprise highly
compressible gas-filled microbubbles. These micrometer-sized particles are typically filled …

Advances in molecular imaging with ultrasound

R Gessner, PA Dayton - Molecular imaging, 2010 - journals.sagepub.com
Ultrasound imaging has long demonstrated utility in the study and measurement of anatomic
features and noninvasive observation of blood flow. Within the last decade, advances in …

Improving sensitivity in ultrasound molecular imaging by tailoring contrast agent size distribution: in vivo studies

JE Streeter, R Gessner, I Miles… - Molecular …, 2010 - journals.sagepub.com
Molecular imaging with ultrasound relies on microbubble contrast agents (MCAs) selectively
adhering to a ligand-specific target. Prior studies have shown that only small quantities of …

[HTML][HTML] Recent developments in dynamic contrast-enhanced ultrasound imaging of tumor angiogenesis

R Saini, K Hoyt - Imaging in medicine, 2014 - ncbi.nlm.nih.gov
Angiogenesis is a critical process for tumor growth and metastatic dissemination. There is
tremendous interest in the development of noninvasive methods for imaging tumor …

Targeted ultrasound contrast agents for ultrasound molecular imaging and therapy

T van Rooij, V Daeichin, I Skachkov… - International journal …, 2015 - Taylor & Francis
Ultrasound contrast agents (UCAs) are used routinely in the clinic to enhance contrast in
ultrasonography. More recently, UCAs have been functionalised by conjugating ligands to …

Targeted ultrasound imaging of cancer: an emerging technology on its way to clinics

F Kiessling, J Bzyl, S Fokong… - Current …, 2012 - ingentaconnect.com
Ultrasound is one of the workhorses in clinical cancer diagnosis. In particular, it is routinely
used to characterize lesions in liver, urogenital tract, head and neck and soft tissues. During …

The effect of amplitude modulation on subharmonic imaging with chirp excitation

S Harput, M Arif, J McLaughlan… - IEEE transactions on …, 2013 - ieeexplore.ieee.org
Subharmonic generation from ultrasound contrast agents depends on the spectral and
temporal properties of the excitation signal. The subharmonic response can be improved by …