Mitochondrial membrane synthesis, remodelling and cellular trafficking

M Messina, FM Vaz, S Rahman - Journal of Inherited Metabolic …, 2025 - Wiley Online Library
Mitochondria are dynamic cellular organelles with complex roles in metabolism and
signalling. Primary mitochondrial disorders are a group of approximately 400 monogenic …

MitoStores: stress-induced aggregation of mitochondrial proteins

P Kaushik, JM Herrmann, KG Hansen - Biological Chemistry, 2025 - degruyter.com
Most mitochondrial proteins are synthesized in the cytosol and post-translationally imported
into mitochondria. If the rate of protein synthesis exceeds the capacity of the mitochondrial …

Mitochondrial CLPB is a pro-survival factor at the onset of granulocytic differentiation of mouse myeloblastic cells

T Wenta, G Wang, T Van Buren, M Zolkiewski… - Apoptosis, 2024 - Springer
Loss-of-function mutations in the CLPB gene lead to congenital neutropenia due to impaired
neutrophil differentiation. CLPB, a member of the AAA+ family of proteins, resides in the …

Monitoring the in vitro import and assembly of mitochondrial precursor proteins into mammalian mitochondria

JJ Crameri, D Stojanovski - Methods in enzymology, 2024 - pubmed.ncbi.nlm.nih.gov
Mitochondrial protein import is a complex process governing the delivery of the organelle's
proteome. This process, in turn, is essential for maintaining mitochondrial function and …