Male fertility throughout life hinges on the successful production of motile sperm, a
developmental process that involves three coordinated transitions: mitosis, meiosis, and …

Gene modification technology has long been beneficial for unraveling the mystery of
biological phenomena. Thus, the advent of the clustered regularly interspaced short …

The formation of fertilisation-competent sperm requires spermatid morphogenesis
(spermiogenesis), a poorly understood program that involves complex coordinated …

Abstract Prssly (Protease, serine-like, Chr Y) and Teyorf1 (Testis expressed, chromosome Y
open reading frame 1) are two acquired single-copy genes located on the distal tip of the …

Background TSN (translin), also called testis brain RNA‐binding protein, binds to TSNAX
(translin‐associated factor X) and is suggested to play diverse roles, such as RNA …

The pancreas is a glandular organ with both endocrine and exocrine functions. Researchers
have investigated the roles of several Rab proteins, which are major regulators of …

Lactate is recognized as a principal energy substrate for male germ cells. Lactate
dehydrogenases (LDHs) catalyze the reversible conversion between pyruvate and lactate …

Introduction This manuscript presents non‐hormonal male contraceptive development in the
context of mitigating risk to investigators and investors. Objective The manuscript uses …

More than 1200 genes have been shown in the database to be expressed predominantly in
the mouse testes. Advances in genome editing technologies such as the CRISPR/Cas9 …

The genetic landscape of male infertility is highly complex. It is estimated that at least 4000
genes are involved in human spermatogenesis, but only few have so far been extensively …