Novel Quinazolinone Derivatives: Potential Synthetic Analogs for the Treatment of Glaucoma, Alzheimer's Disease and Diabetes Mellitus
Quinazolinones, which represent an important part of nitrogen‐containing six‐membered
heterocyclic compounds, are frequently used in drug design due to their wide biological …
heterocyclic compounds, are frequently used in drug design due to their wide biological …
Synthesis of new carboxylates and sulfonates containing thiazolidin-4-one ring and evaluation of inhibitory properties against some metabolic enzymes
A series of thizaolidin-4-one derivatives (3a-o) was synthesized with excellent yield (94–
97%) and the structures of the compounds were characterized with Fourier-transform …
97%) and the structures of the compounds were characterized with Fourier-transform …
Synthesis and Anticancer Activity of Novel Derivatives of α,β‐Unsaturated Ketones Based on Oleanolic Acid: in Vitro and in Silico Studies against Prostate Cancer …
H Şenol, M Ghaffari‐Moghaddam, Ş Bulut… - Chemistry & …, 2023 - Wiley Online Library
Herein, new derivatives of α, β‐unsaturated ketones based on oleanolic acid (4 a–i) were
designed, synthesized, characterized, and tested against human prostate cancer (PC3) …
designed, synthesized, characterized, and tested against human prostate cancer (PC3) …
Synthesis, characterization, molecular docking and in vitro anti-cancer activity studies of new and highly selective 1, 2, 3-triazole substituted 4-hydroxybenzohyrdazide …
In this study, 16 new hybrid compounds 6 (ah) and 7 (ah) were synthesized starting from
methylparaben. These new compounds consist of eight 1, 2, 3-triazole-arylidenehydrazide …
methylparaben. These new compounds consist of eight 1, 2, 3-triazole-arylidenehydrazide …
Synthesis, characterization and molecular docking studies of highly selective new hydrazone derivatives of anthranilic acid and their ring closure analogue Quinazolin …
In this study, new Schiff bases derived from anthranilic acid hydrazide (3a-j) and quinazolin-
4 (3H)-one (4a-j) were synthesized with high yields (99-90%) and characterized by FTIR …
4 (3H)-one (4a-j) were synthesized with high yields (99-90%) and characterized by FTIR …
New Anthranilic Acid Hydrazones as Fenamate Isosteres: Synthesis, Characterization, Molecular Docking, Dynamics & in Silico ADME, in Vitro Anti‐Inflammatory …
H Şenol, Z Çağman… - Chemistry & …, 2023 - Wiley Online Library
In this study, twenty new anthranilic acid hydrazones 6–9 (a–e) were synthesized and their
structures were characterized by Fourier‐transform Infrared (FT‐IR), Nuclear Magnetic …
structures were characterized by Fourier‐transform Infrared (FT‐IR), Nuclear Magnetic …
Synthesis, Characterization, Molecular Docking and in vitro Biological Studies of Thiazolidin‐4‐one Derivatives as Anti‐Breast‐Cancer Agents
In this study, 16 new compounds were synthesized starting from methylparaben. These new
compounds consist of eight arylidenehydrazide derivatives and eight thiazolidin‐4‐on …
compounds consist of eight arylidenehydrazide derivatives and eight thiazolidin‐4‐on …
3‐Amino‐thiophene‐2‐carbohydrazide derivatives as anti Colon cancer Agents: synthesis, characterization, in‐Silico and in‐Vitro Biological activity studies
In this study, starting from 3‐amino‐thiophene‐2‐carboxylic acid methyl ester, eighteen new
arylidenehydrazide derivatives (4–21) were synthesized. To determine cytotoxic activity of …
arylidenehydrazide derivatives (4–21) were synthesized. To determine cytotoxic activity of …
Novel quinazoline–chromene hybrids as anticancer agents: Synthesis, biological activity, molecular docking, dynamics and ADME studies
In this study, new quinazoline–chromene hybrid compounds were synthesized. The
cytotoxic effects on cell viability of the hybrid compounds were tested against A549 human …
cytotoxic effects on cell viability of the hybrid compounds were tested against A549 human …
Rational design and eco-friendly one-pot multicomponent synthesis of novel ethylidenehydrazineylthiazol-4 (5H)-ones as potential apoptotic inducers targeting wild …
A novel series of ethylidenehydrazineylthiazol-4 (5H)-ones were synthesized using various
eco-friendly one-pot multicomponent synthetic techniques. The anticancer activity of …
eco-friendly one-pot multicomponent synthetic techniques. The anticancer activity of …