Dietary vs. pharmacological doses of zinc: A clinical review

HO Santos, FJ Teixeira, BJ Schoenfeld - Clinical nutrition, 2020 - Elsevier
Zinc deficiency has a global impact on health in both developing and developed countries,
especially among children and the elderly. By modulating anti-inflammatory and antioxidant …

[HTML][HTML] Targeting the gut barrier for the treatment of alcoholic liver disease

Z Zhou, W Zhong - Liver research, 2017 - Elsevier
Alcohol consumption remains one of the predominant causes of liver disease and liver-
related death worldwide. Intriguingly, dysregulation of the gut barrier is a key factor …

Dietary advanced glycation end products modify gut microbial composition and partially increase colon permeability in rats

W Qu, X Yuan, J Zhao, Y Zhang, J Hu… - Molecular nutrition & …, 2017 - Wiley Online Library
Scope The adverse impacts of dietary advanced glycation end products (AGEs) on health
are currently of interest. These compounds are inevitably formed during thermal food …

Zinc enhances intestinal epithelial barrier function through the PI3K/AKT/mTOR signaling pathway in Caco-2 cells

Y Shao, PG Wolf, S Guo, Y Guo, HR Gaskins… - The Journal of …, 2017 - Elsevier
Zinc plays an important role in maintaining intestinal barrier function as well as modulating
cellular signaling recognition and protein kinase activities. The phosphatidylinositol 3-kinase …

The gut–liver axis in chronic liver disease: A macrophage perspective

K De Muynck, B Vanderborght, H Van Vlierberghe… - Cells, 2021 - mdpi.com
Chronic liver disease (CLD) is a growing health concern which accounts for two million
deaths per year. Obesity, alcohol overconsumption, and progressive cholestasis are …

Nutrition and alcoholic liver disease: effects of alcoholism on nutrition, effects of nutrition on alcoholic liver disease, and nutritional therapies for alcoholic liver disease

S Dasarathy - Clinics in liver disease, 2016 - liver.theclinics.com
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Zinc deficiency as a mediator of toxic effects of alcohol abuse

AV Skalny, MG Skalnaya, AR Grabeklis… - European journal of …, 2018 - Springer
Objective To review data on the role of ethanol-induced alteration of Zn homeostasis in
mediation of adverse effects of alcohol abuse. Methods The scholarly published articles on …

[HTML][HTML] Development, prevention, and treatment of alcohol-induced organ injury: the role of nutrition

S Barve, SY Chen, I Kirpich, WH Watson… - Alcohol research …, 2017 - ncbi.nlm.nih.gov
Alcohol and nutrition have the potential to interact at multiple levels. For example, heavy
alcohol consumption can interfere with normal nutrition, resulting in overall malnutrition or in …

Over-expression of intestinal alkaline phosphatase attenuates atherosclerosis

SS Ghosh, J Wang, PJ Yannie, RC Cooper… - Circulation …, 2021 - Am Heart Assoc
Rationale: Intestinal alkaline phosphatase (IAP) is secreted by enterocytes and is present on
the apical surface. It not only detoxifies bacterial endotoxin lipopolysaccharide (LPS) in the …

Concurrent gut transcriptome and microbiota profiling following chronic ethanol consumption in nonhuman primates

T Barr, S Sureshchandra, P Ruegger, J Zhang… - Gut …, 2018 - Taylor & Francis
Alcohol use disorder (AUD) results in increased intestinal permeability, nutrient
malabsorption, and increased risk of colorectal cancer (CRC). Our understanding of the …