The dual role of immune response in acetaminophen hepatotoxicity: Implication for immune pharmacological targets

L Gong, L Liao, X Dai, X Xue, C Peng, Y Li - Toxicology Letters, 2021 - Elsevier
Acetaminophen (APAP), one of the most widely used antipyretic and analgesic drugs,
principally contributes to drug-induced liver injury when taken at a high dose. APAP-induced …

Cerium oxide nanoparticles improve liver regeneration after acetaminophen-induced liver injury and partial hepatectomy in rats

B Córdoba-Jover, A Arce-Cerezo, J Ribera… - Journal of …, 2019 - Springer
Background and aims Cerium oxide nanoparticles are effective scavengers of reactive
oxygen species and have been proposed as a treatment for oxidative stress-related …

Hepatoprotective effects of fruits pulp, seed, and peel against chemical-induced toxicity: insights from in vivo studies

H Kumar, DS Dhanjal, S Guleria, E Nepovimova… - Food and Chemical …, 2024 - Elsevier
The liver is a vital organ in human physiology positioned in the upper right quadrant of the
peritoneal cavity, which plats a critical role in metabolic processes, detoxification of various …

Protective effects of Artemisia judaica extract compared to metformin against hepatorenal injury in high-fat diet/streptozotocine-induced diabetic rats

G Albasher, M Alwahaibi, MM Abdel-Daim… - … science and pollution …, 2020 - Springer
Diabetes mellitus (DM) is one of the most dangerous incurable diseases that affects a large
number of people worldwide. Artemisia species have various protective activities and are …

Allicin mitigates hepatic injury following cyclophosphamide administration via activation of Nrf2/ARE pathways and through inhibition of inflammatory and apoptotic …

D Sun, C Sun, G Qiu, L Yao, J Yu, H Al Sberi… - … Science and Pollution …, 2021 - Springer
Abstract Treatment with anti-neoplastic agents, including cyclophosphamide (CP), is
associated with several adverse reactions. Here, we distinguished the potential protective …

Graviola mitigates acetic acid–induced ulcerative colitis in rats: insight on apoptosis and Wnt/Hh signaling crosstalk

MG Helal, AG Abd Elhameed - Environmental Science and Pollution …, 2021 - Springer
In this study, we elucidated the potential protective effects of graviola leaves, compared with
sulfasalazine, against acetic acid (AA)–induced ulcerative colitis (UC) in rats. Twenty-eight …

Nephroprotective Role of Beta vulgaris L. Root Extract against Chlorpyrifos‐Induced Renal Injury in Rats

G Albasher, R Almeer, S Alarifi… - Evidence‐Based …, 2019 - Wiley Online Library
Organophosphorus pesticides (OPs) are widely used for agricultural and housekeeping
purposes. Exposure to OPs is associated with the progression of several health issues …

Bioactive Compounds of Soursop (Annona muricata L.) Fruit

LM Anaya Esparza, E Montalvo-González - Bioactive compounds in …, 2020 - Springer
Soursop (Annona muricata) belongs to the family Annonaceae and is widely distributed and
commercially cultivated in tropical and subtropical climates around the world. The stem …

The Allium triquetrum L. Leaves Mitigated Hepatotoxicity and Nephrotoxicity Induced by Lead Acetate in Wistar Rats

L Kahalerras, I Otmani, C Abdennour - Biological trace element research, 2022 - Springer
The aim of this study was to scrutinize the possible mitigating role of leaves' Allium
triquetrum L. against the toxicity of lead acetate on liver and kidney markers of Wistar rat …

Guiqi baizhu decoction alleviates radiation inflammation in rats by modulating the composition of the gut microbiota

LY Zhang, T Zhou, YM Zhang, XM Xu… - Evidence‐Based …, 2020 - Wiley Online Library
The gut microbiota is important in metabolism and immune modulation, and compositional
disruption of the gut microbiota population is closely associated with inflammation caused by …