Per‐and polyfluoroalkyl substance toxicity and human health review: Current state of knowledge and strategies for informing future research
Reports of environmental and human health impacts of per‐and polyfluoroalkyl substances
(PFAS) have greatly increased in the peer‐reviewed literature. The goals of the present …
(PFAS) have greatly increased in the peer‐reviewed literature. The goals of the present …
Legacy and emerging per-and polyfluoroalkyl substances: analytical techniques, environmental fate, and health effects
RA Brase, EJ Mullin, DC Spink - International journal of molecular …, 2021 - mdpi.com
Due to their unique chemical properties, per-and polyfluoroalkyl substances (PFAS) have
been used extensively as industrial surfactants and processing aids. While several types of …
been used extensively as industrial surfactants and processing aids. While several types of …
Risk to human health related to the presence of perfluoroalkyl substances in food
EFSA Panel on Contaminants in the Food Chain … - EFSA …, 2020 - Wiley Online Library
Abstract The European Commission asked EFSA for a scientific evaluation on the risks to
human health related to the presence of perfluoroalkyl substances (PFAS s) in food. Based …
human health related to the presence of perfluoroalkyl substances (PFAS s) in food. Based …
In vitro activity of a panel of per-and polyfluoroalkyl substances (PFAS), fatty acids, and pharmaceuticals in peroxisome proliferator-activated receptor (PPAR) alpha …
N Evans, JM Conley, M Cardon, P Hartig… - Toxicology and applied …, 2022 - Elsevier
Data demonstrate numerous per-and polyfluoroalkyl substances (PFAS) activate
peroxisome proliferator-activated receptor alpha (PPARα), however, additional work is …
peroxisome proliferator-activated receptor alpha (PPARα), however, additional work is …
Systemic PFOS and PFOA exposure and disturbed lipid homeostasis in humans: what do we know and what not?
S Fragki, H Dirven, T Fletcher… - Critical reviews in …, 2021 - Taylor & Francis
Associations between per-and polyfluoroalkyl substances (PFASs) and increased blood
lipids have been repeatedly observed in humans, but a causal relation has been debated …
lipids have been repeatedly observed in humans, but a causal relation has been debated …
[HTML][HTML] Hexafluoropropylene oxide-dimer acid (HFPO-DA or GenX) alters maternal and fetal glucose and lipid metabolism and produces neonatal mortality, low …
Hexafluoropropylene oxide dimer acid (HFPO-DA or GenX) is an industrial replacement for
the straight-chain perfluoroalkyl substance (PFAS), perfluorooctanoic acid (PFOA) …
the straight-chain perfluoroalkyl substance (PFAS), perfluorooctanoic acid (PFOA) …
[HTML][HTML] Changes in plasma levels of per-and polyfluoroalkyl substances (PFAS) are associated with changes in plasma lipids-A longitudinal study over 10 years
L Dunder, PM Lind, S Salihovic, J Stubleski… - Environmental …, 2022 - Elsevier
Background Associations between per-and polyfluoroalkyl substances (PFAS), mainly PFOS
and PFOA, and increased blood lipids have been reported primarily from cross-sectional …
and PFOA, and increased blood lipids have been reported primarily from cross-sectional …
[HTML][HTML] Exposure to low-dose perfluorooctanoic acid promotes hepatic steatosis and disrupts the hepatic transcriptome in mice
B Attema, AWF Janssen, D Rijkers… - Molecular …, 2022 - Elsevier
Objective Perfluoroalkyl substances (PFAS) are man-made chemicals with demonstrated
endocrine-disrupting properties. Exposure to perfluorooctanoic acid (PFOA) has been linked …
endocrine-disrupting properties. Exposure to perfluorooctanoic acid (PFOA) has been linked …
Environmental perfluoroalkyl acid exposures are associated with liver disease characterized by apoptosis and altered serum adipocytokines
Exposures to perfluoroalkyl substances (PFAS) including perfluoroalkyl acids (PFAAs) are
associated with increased liver enzymes in cohort studies including the C8 Health Study. In …
associated with increased liver enzymes in cohort studies including the C8 Health Study. In …
Risk assessment of per‐and polyfluoroalkyl substance mixtures: A relative potency factor approach
W Bil, M Zeilmaker, S Fragki, J Lijzen… - Environmental …, 2021 - Wiley Online Library
Per‐and polyfluoroalkyl substances (PFAS) often occur together as contamination in
exposure media such as drinking water or food. The relative potency factor (RPF) …
exposure media such as drinking water or food. The relative potency factor (RPF) …