Near-infrared spectroscopy (NIRS) has potential as a noninvasive brain monitor across a
spectrum of disorders. In the last decade, there has been a rapid expansion of clinical …

Near-infrared spectroscopy (NIRS) measurements of cytochrome-c-oxidase (CCO) have the
potential to yield crucial information about cerebral metabolism at the patient bedside …

Cerebral blood flow (CBF) and cerebral autoregulation (CA) are critically important to
maintain proper brain perfusion and supply the brain with the necessary oxygen and energy …

Oxygen treatment has been a cornerstone of acute medical care for numerous pathological
states. Initially, this was supported by the assumed need to avoid hypoxaemia and tissue …

An association between hypoxemia and poor outcomes from traumatic brain injury (TBI) is
well documented. However, it is unclear whether hyperoxygenation is beneficial. This …

Object Oxygen delivered in supraphysiological amounts is currently under investigation as a
therapy for severe traumatic brain injury (TBI). Hyperoxia can be delivered to the brain under …

Object Preclinical and clinical investigations indicate that the positive effect of hyperbaric
oxygen (HBO 2) for severe traumatic brain injury (TBI) occurs after rather than during …

Limits on perceptual capacity result in various phenomena of inattentional blindness. Here
we propose a neurophysiological account attributing these perceptual capacity limits directly …

Measurement of intracranial pressure (ICP) and mean arterial pressure (MAP) is used to
derive cerebral perfusion pressure (CPP) and to guide targeted therapy of acute brain injury …

We re-determined the near infrared (NIR) spectral signatures (650–980 nm) of the different
cytochrome c oxidase redox centres, in the process separating them into their component …