DNA N6-methyladenine: a new epigenetic mark in eukaryotes?

GZ Luo, MA Blanco, EL Greer, C He… - Nature reviews Molecular …, 2015 - nature.com
Abstract DNA N 6-adenine methylation (N 6-methyladenine; 6mA) in prokaryotes functions
primarily in the host defence system. The prevalence and significance of this modification in …

Epigenetic gene regulation in the bacterial world

J Casadesús, D Low - Microbiology and molecular biology …, 2006 - Am Soc Microbiol
Like many eukaryotes, bacteria make widespread use of postreplicative DNA methylation for
the epigenetic control of DNA-protein interactions. Unlike eukaryotes, however, bacteria use …

[HTML][HTML] N6-methyladenine DNA modification in Drosophila

G Zhang, H Huang, D Liu, Y Cheng, X Liu, W Zhang… - Cell, 2015 - cell.com
Summary DNA N 6-methyladenine (6mA) modification is commonly found in microbial
genomes and plays important functions in regulating numerous biological processes in …

N6-deoxyadenosine methylation in mammalian mitochondrial DNA

Z Hao, T Wu, X Cui, P Zhu, C Tan, X Dou, KW Hsu… - Molecular cell, 2020 - cell.com
Summary N 6-Methyldeoxyadenosine (6mA) has recently been shown to exist and play
regulatory roles in eukaryotic genomic DNA (gDNA). However, the biological functions of …

Plant peptides govern terminal differentiation of bacteria in symbiosis

W Van de Velde, G Zehirov, A Szatmari, M Debreczeny… - Science, 2010 - science.org
Legume plants host nitrogen-fixing endosymbiotic Rhizobium bacteria in root nodules. In
Medicago truncatula, the bacteria undergo an irreversible (terminal) differentiation mediated …

DNA methyltransferases and epigenetic regulation in bacteria

S Adhikari, PD Curtis - FEMS microbiology reviews, 2016 - academic.oup.com
Epigenetics is a change in gene expression that is heritable without a change in DNA
sequence itself. This phenomenon is well studied in eukaryotes, particularly in humans for …

Taxonomy of Rhizobiaceae revisited: proposal of a new framework for genus delimitation

N Kuzmanović, C Fagorzi… - … of systematic and …, 2022 - microbiologyresearch.org
The alphaproteobacterial family Rhizobiaceae is highly diverse, with 168 species with
validly published names classified into 17 genera with validly published names. Most …

Antibiotic resistance and epigenetics: more to it than meets the eye

D Ghosh, B Veeraraghavan, R Elangovan… - Antimicrobial agents …, 2020 - Am Soc Microbiol
The discovery of antibiotics in the last century is considered one of the most important
achievements in the history of medicine. Antibiotic usage has significantly reduced morbidity …

Roles of DNA adenine methylation in regulating bacterial gene expression and virulence

DA Low, NJ Weyand, MJ Mahan - Infection and immunity, 2001 - Am Soc Microbiol
Background. Based on the organization of 10 amino acid domains present in MTases, Dam
is classified in the α group (Fig. 1)(46). Dam homologues are widespread among enteric …

N6‐methyladenine: the other methylated base of DNA

D Ratel, JL Ravanat, F Berger, D Wion - Bioessays, 2006 - Wiley Online Library
Contrary to mammalian DNA, which is thought to contain only 5‐methylcytosine (m5C),
bacterial DNA contains two additional methylated bases, namely N6‐methyladenine (m6A) …