Learning effective molecular feature representation to facilitate molecular property prediction
is of great significance for drug discovery. Recently, there has been a surge of interest in pre …

Iminosugars are naturally occurring carbohydrate analogues known since 1967. These
natural compounds and hundreds of their synthetic derivatives prepared over five decades …

Qingfei Paidu decoction (QFPD), a multi-component herbal formula, has been widely used
to treat COVID-19 in China. However, its active compounds and mechanisms of action are …

Following the discovery of plastics in the human placenta, this study evaluated the toxicity of
ten different nanoplastics (NPs) in the human placenta. Since the placenta performs …

Tuberculosis is caused by Mycobacterium tuberculosis (MTB) and is the leading cause of
death from infectious diseases in the World. The search for new antituberculosis drugs is a …

ABSTRACT Isoindoline-1, 3-dione, also referred as phthalimide, has gained recognition as
promising pharmacophore due to the documented biological activities of its derivatives …

Probes that covalently label protein targets facilitate the identification of ligand-binding sites.
Lysine residues are prevalent in the proteome, making them attractive substrates for …

Liver fibrosis results from the hepatic accumulation of the extracellular matrix accompanied
by a failure of the mechanisms responsible for matrix dissolution. Pathogenesis of liver …

Breast cancer (Bc a) is the prominent, most commonly detected, and the leading cause of
mortality among women. Estrogen receptor alpha (ERα) is considered an important receptor …

Leishmaniasis is a severe disease caused by protozoan parasites of the genus Leishmania
and it is accountable for sizable morbidity and mortality worldwide. So far, no effective …