Lipid metabolism and endometrial receptivity

T Yang, J Zhao, F Liu, Y Li - Human Reproduction Update, 2022 - academic.oup.com
BACKGROUND Obesity has now been recognized as a high-risk factor for reproductive
health. Although remarkable advancements have been made in ART, a considerable …

Implications of high-density cholesterol metabolism for oocyte biology and female fertility

A Arias, A Quiroz, N Santander, E Morselli… - Frontiers in Cell and …, 2022 - frontiersin.org
Cholesterol is an essential component of animal cells. Different regulatory mechanisms
converge to maintain adequate levels of this lipid because both its deficiency and excess …

Granulosa cell metabolism at ovulation correlates with oocyte competence and is disrupted by obesity and aging

A Morimoto, RD Rose, KM Smith, DT Dinh… - Human …, 2024 - academic.oup.com
STUDY QUESTION Is oocyte developmental competence associated with changes in
granulosa cell (GC) metabolism? SUMMARY ANSWER GC metabolism is regulated by the …

[HTML][HTML] Oocyte aging: a multifactorial phenomenon in a unique cell

P Kordowitzki, S Graczyk, A Haghani… - Aging and …, 2024 - ncbi.nlm.nih.gov
The oocyte is considered to be the largest cell in mammalian species. Women hoping to
become pregnant face a ticking biological clock. This is becoming increasingly challenging …

Obesity management in women of reproductive age

A Andreu, G Casals, I Vinagre, L Flores - Endocrinología, Diabetes y …, 2023 - Elsevier
With the increasing prevalence of obesity among women of reproductive age, the
detrimental effects on maternal and neonatal health are increasing. The objective of this …

Bariatric surgery and reproduction-implications for gynecology and obstetrics

IA Babarinsa, M Bashir, HAR Ahmed, B Ahmed… - Best Practice & …, 2023 - Elsevier
As the rates of obesity continue to rise across the world, there has been an increasing resort
to bariatric surgery amongst the options for treatment. Through the reproductive lifespan …

Alteration of the embryonic microenvironment and sex-specific responses of the preimplantation embryo related to a maternal high-fat diet in the rabbit model

S Calderari, C Archilla, L Jouneau, N Daniel… - … Origins of Health and …, 2023 - cambridge.org
The maternal metabolic environment can be detrimental to the health of the offspring. In a
previous work, we showed that maternal high-fat (HH) feeding in rabbit induced sex …

Emerging therapeutic strategies to mitigate female and male reproductive aging

YE Winstanley, JS Stables, MB Gonzalez, T Umehara… - Nature Aging, 2024 - nature.com
People today are choosing to have children later in life, often in their thirties and forties,
when their fertility is in decline. We sought to identify and compile effective methods for …

Obesity and reproduction

A Armstrong, M Berger, Z Al-Safi - Current Opinion in Obstetrics …, 2022 - journals.lww.com
Obesity and reproduction : Current Opinion in Obstetrics and Gynecology Obesity and
reproduction : Current Opinion in Obstetrics and Gynecology Log in or Register Subscribe to …

The impact of a maternal and offspring obesogenic diet on daughter's oocyte mitochondrial ultrastructure and bioenergetic responses. Insights from an outbred mouse …

I Xhonneux, WFA Marei, B Meulders, S Andries… - Frontiers in …, 2023 - frontiersin.org
Obesity affects oocyte mitochondrial functions and reduces oocyte quality and fertility.
Obesity may also increase the risk of metabolic disorders in the offspring. Children are likely …