Research progress in targeted therapy and immunotherapy for gastric cancer

X Li, J Xu, J Xie, W Yang - Chinese Medical Journal, 2022 - journals.lww.com
Gastric cancer (GC) is one of the most common malignant tumors worldwide. Its incidence
ranks the 5th among all malignant tumors globally, and it is the 3rd leading cause of death …

Successes and failures of angiogenesis blockade in gastric and gastro-esophageal junction adenocarcinoma

M Salati, F Caputo, A Bocconi, S Cerri… - Frontiers in …, 2022 - frontiersin.org
Gastric and gastro-esophageal junction adenocarcinoma (GEA) remains a considerable
major public health problem worldwide, being the fifth most common cancer with a fatality-to …

A new biomarker for the early diagnosis of gastric cancer: gastric juice-and serum-derived SNCG

Y Pan, Y Zheng, J Yang, Y Wei, H Wu, S Liu… - Future …, 2022 - Taylor & Francis
Aim: To explore the possibility of gastric juice (GJ)-and serum-derived SNCG as a potential
biomarker for the early diagnosis of gastric cancer (GC). Materials & methods: GJ and serum …

Comprehensive analysis of the oncogenic roles of vascular endothelial growth factors and their receptors in stomach adenocarcinoma

J Li, T Han - Heliyon, 2023 - cell.com
Background Vascular endothelial growth factors (VEGFs) and their receptors (VEGFRs) play
complicated oncogenic roles in multiple tumors by initiating and promoting tumor …

Long non-coding RNA ARAP1-AS1 contributes to cell proliferation and migration in clear cell renal cell carcinoma via the miR-361-3p/placental growth factor axis

L Zhong, X Zhong - Bioengineered, 2021 - Taylor & Francis
Clear cell renal cell carcinoma (ccRCC) is an aggressive malignancy with a poor prognosis.
Therefore, investigating the molecular mechanism of ccRCC is important for ccRCC …

Real-World Effectiveness and Safety of Ramucirumab as a Second-Line Treatment for Patients with Unresectable Advanced or Metastatic Gastric/Gastroesophageal …

X Zhang, L Zhou, C Zhou, L Shen - Advances in Therapy, 2024 - Springer
Introduction Gastric cancer has the highest incidence and mortality in Eastern Asia. The
efficacy and safety of ramucirumab (RAM) monotherapy or in combination with paclitaxel …

Correlation between tumor response and survival outcomes in patients with advanced gastric cancer receiving ramucirumab and paclitaxel as second-line therapy

G Roviello, C Martina, C Winchler… - Journal of …, 2023 - Springer
Background Gastric cancer (GC) is one of the leading causes of cancer-related death
worldwide. The first-line treatment for GC is a combination of platinum and fluoropyrimidine …

Unveiling promising targets in gastric cancer therapy: A comprehensive review

W Li, J Wei, M Cheng, M Liu - Molecular Therapy Oncology, 2024 - cell.com
Gastric cancer (GC) poses a significant global health challenge, ranking fifth in incidence
and third in mortality among all malignancies worldwide. Its insidious onset, aggressive …

PlGF knockdown attenuates hypoxia-induced stimulation of cell proliferation and glycolysis of lung adenocarcinoma through inhibiting Wnt/β-catenin pathway

W Zhang, Y Zhang, W Zhou, F Qian, M Hu… - Cancer Cell …, 2021 - Springer
Background Angiogenic placental growth factor (PlGF) plays a role in hypoxia-induced
angiogenesis. Here, we aimed to investigate the biological roles of PlGF in cell proliferation …

[HTML][HTML] 晚期胃癌分子靶向与免疫治疗相关性研究

刘聪, 马鹏 - Advances in Clinical Medicine, 2022 - hanspub.org
胃癌(gastric cancer, GC) 是一种广泛存在于全球的恶性肿瘤, 每年约有一千万到两千万的GC
患者, 其中以老年人居多, 在我国, 胃癌的发病率和死亡率均排在第二位. 由于早期胃癌往往没有 …