The p38 MAPK protein kinases affect a variety of intracellular responses, with well-
recognized roles in inflammation, cell-cycle regulation, cell death, development …

Mitogen-activated protein kinases (MAPK) are intracellular signaling molecules involved in
cytokine synthesis. Several classes of mammalian MAPK have been identified, including …

The aim of this study was to examine whether salivary exosomal miRNAs could be identified
as aging biomarkers. Fifteen young healthy volunteers (median age, 21.0 years) and 13 old …

Dental pulp cells can differentiate toward an odontoblastic phenotype to produce reparative
dentin beneath caries lesions. However, the mechanisms involved in pulp cell differentiation …

Objectives Periodontitis is an inflammatory immune disease that causes periodontal tissue
loss. Inflammatory immunity and bone metabolism are closely related to periodontitis. The …

Tristetraprolin (TTP) is a well-characterized, zinc finger-containing, RNA-binding protein.
TTP targets tumor necrosis factor α for degradation via the 3′ untranslated region (3 …

Proteoglycans are core proteins associated with carbohydrate/sugar moieties that are highly
variable in disaccharide composition, which dictates their function. These carbohydrates are …

Recently, new treatment approaches have been developed to target the host component of
periodontal disease. This review aims at providing updated information on host-modulating …

Background Periodontitis is a chronic infection initiated by oral bacterial and their virulence
factors, yet the severity of periodontitis is largely determined by the dysregulated host …

Fine particulate air pollutants, mainly their organic fraction, have been demonstrated to be
associated with cardiovascular and respiratory health problems. Puerto Rico has been …