Akt kinase, a member of AGC kinases, is important in many cellular functions including
proliferation, migration, cell growth and metabolism. There are three known Akt isoforms …

Background Diabetes mellitus is a chronic metabolic disorder associated with persistent
increased level of glucose in the blood. According to a report by World Health Organisation …

Patients with preexisting cardiovascular disease or those at high risk for developing the
condition are often offered exercise as a form of therapy. Patients with cancer who are at an …

Objective: The purpose of this study was to investigate the effect of 12 weeks aerobic
training on the expression of AKT1 and mTORc1 genes in the left ventricle of T2DM rats …

Cardiovascular diseases are the most common cause of death in the world. One of the major
causes of cardiac death is excessive apoptosis. However, multiple pathways through …

Exercise training is considered a benefit to heart function, but the benefit in aging hearts
remains unknown. Activation of the PI3K-Akt survival pathway and suppression of …

As one of the most serious complications of diabetes, diabetic cardiomyopathy (DCM)
imposes a huge burden on individuals and society, and represents a major public health …

Coronary artery disease (CAD) is a critical cardiovascular disease and a cause of high
morbidity and mortality in this world. Hyperhomocysteinemia (HHcy) has been suggested as …

The present study investigated the possible cardioprotective effects of GLP1 and SGLT2i
against diabetic cardiomyopathy (DCM) in type 2 diabetic rats and the possible underlying …

Patients with Alzheimer's disease have increased risk of developing heart disease, which
therefore highlights the need for strategies aiming at reducing Alzheimer's disease-related …