Small molecule active site directed tools for studying human caspases

M Poreba, A Szalek, P Kasperkiewicz, W Rut… - Chemical …, 2015 - ACS Publications
Caspases are proteases of clan CD and were described for the first time more than two
decades ago. They play critical roles in the control of regulated cell death pathways …

Recent advances in electrochemical and electrochemiluminescence based determination of the activity of caspase-3

B Khalilzadeh, N Shadjou, HN Charoudeh… - Microchimica Acta, 2017 - Springer
Abstract Caspases, especially caspase-3, play a critical role in the intrinsic and extrinsic
pathways of apoptosis. In addition, caspase-3 is involved in mental disorders like Alzheimer …

A signal-on electrochemical biosensor for evaluation of caspase-3 activity and cell apoptosis by the generation of molecular electrocatalysts on graphene electrode …

D Deng, Y Hao, S Yang, Q Han, L Liu, Y Xiang… - Sensors and Actuators B …, 2019 - Elsevier
Caspase-3 is believed to be important for diagnosis and prognosis of apoptosis-relative
diseases, serving as a reliable molecular biomarker and therapeutic target. In this work, we …

Multiwalled carbon nanotube/Fe-doped ZnO-based sensors for droplet electrochemical detection and degradation monitoring of brilliant green

F Aslam, A Shah, N Ullah, S Munir - ACS Applied Nano Materials, 2023 - ACS Publications
The present research work aims to contribute toward the sustainable development goal of
water cleanliness by monitoring and removing toxic effluents from wastewater. Herein, we …

Tripeptide Derivative-Modified Glassy Carbon Electrode: A Novel Electrochemical Sensor for Sensitive and Selective Detection of Cd2+ Ions

T Kokab, A Shah, J Nisar, AM Khan, SB Khan… - ACS …, 2020 - ACS Publications
AN-[(Benzyloxy) carbonyl]-l-alanyl-l-prolyl-l-leucine-N-cyclohexylcyclohexanamine (Cbz-
APL) tripeptide-coated glassy carbon electrode (GCE)-based sensor was used for sensitive …

Impedimetric biosensor for assay of caspase-3 activity and evaluation of cell apoptosis using self-assembled biotin-phenylalanine network as signal enhancer

N Xia, Y Huang, Z Cui, S Liu, D Deng, L Liu… - Sensors and Actuators B …, 2020 - Elsevier
This work demonstrates that the biotinylated phenylalanine (biotin-Phe) monomers can be
self-assembled into biotin-Phe nanoparticle (biotin-FNP) under mild conditions. The …

[HTML][HTML] Signal-on detection of caspase-3 with methylene blue-loaded metal-organic frameworks as signal reporters

Y Huang, J Wang, Y Xu, J Zhang, N Xia - Molecules, 2024 - mdpi.com
In this work, we report on an electrochemical method for the signal-on detection of caspase-
3 and the evaluation of apoptosis based on the biotinylation reaction and the signal …

Development of tribenzamide functionalized electrochemical sensor for femtomolar level sensing of multiple inorganic water pollutants

T Kokab, A Manzoor, A Shah, HM Siddiqi, J Nisar… - Electrochimica …, 2020 - Elsevier
A novel tribenzamides derivative N-{4-[2-(1, 3-Benzoxazolyl)] phenyl}-3, 5-N, N′-bis (4-
hexyloxybenzoyl) benzamide (BOC6), containing three amide groups, was successfully …

Electroanalysis of Ibuprofen and Its Interaction with Bovine Serum Albumin

M Dilshad, A Shah, S Munir - Molecules, 2022 - mdpi.com
The current work presents a sensitive, selective, cost-effective, and environmentally benign
protocol for the detection of ibuprofen (IBP) by an electrochemical probe made of a glassy …

A signal-on electrochemical strategy for protease detection based on the formation of ATCUN-Cu (II)

N Xia, P Peng, S Wang, J Du, G Zhu, W Du… - Sensors and Actuators B …, 2016 - Elsevier
Amino terminal Cu (II)-and Ni (II)-binding (ATCUN) motif is included in a protein or peptide
with a structural characterization comprising of a free NH 2-terminus, a histidine residue in …