In vitro cell cultures are an important tool for obtaining insights into cellular processes in an
isolated system and a supplement to in vivo animal experiments. While primary dissociated …

The blood–brain barrier, which is formed by the endothelial cells that line cerebral
microvessels, has an important role in maintaining a precisely regulated microenvironment …

The specifically regulated restrictive permeability barrier to cells and molecules is the most
important feature of the blood–brain barrier (BBB). The aim of this review was to summarize …

Three main barrier layers at the interface between blood and tissue protect the central
nervous system (CNS): the endothelium of brain capillaries, and the epithelia of the choroid …

The blood-labyrinth barrier (BLB) in the stria vascularis is a highly specialized capillary
network that controls exchanges between blood and the intrastitial space in the cochlea. The …

Blood–brain barrier (BBB) pathology leads to neurovascular disorders and is an important
target for therapies. However, the study of BBB pathology is difficult in the absence of …

The central nervous system (CNS) is a perfectly regulated environment with conditions far
different from those in the rest of the organism. Even slight changes in this machinery affect …

The blood brain barrier (BBB) evolved to preserve the microenvironment of the highly
excitable neuronal cells to allow for action potential generation and propagation. Intricate …

The first successful isolation of cerebral microvessels from rat brain some 30 years ago
opened the way to the development of in vitro models of the blood-brain barrier (BBB), which …

The blood–brain barrier (BBB) is a cellular and physical barrier with a crucial role in
homeostasis of the brain extracellular environment. It controls the imports of nutrients to the …