The bioelectrical properties of bone tissue

BC Heng, Y Bai, X Li, Y Meng, Y Lu… - Animal models and …, 2023 - Wiley Online Library
Understanding the bioelectrical properties of bone tissue is key to developing new treatment
strategies for bone diseases and injuries, as well as improving the design and fabrication of …

Organ tropism in solid tumor metastasis: an updated review

K Mortezaee - Future Oncology, 2021 - Taylor & Francis
Tumors are equipped with a highly complex machinery of interrelated events so as to adapt
to hazardous conditions, preserve a growing cell mass and thrive at the site of metastasis …

Sarm1 activation produces cADPR to increase intra-axonal Ca++ and promote axon degeneration in PIPN

Y Li, MF Pazyra-Murphy, D Avizonis… - Journal of Cell …, 2021 - rupress.org
Cancer patients frequently develop chemotherapy-induced peripheral neuropathy (CIPN), a
painful and long-lasting disorder with profound somatosensory deficits. There are no …

Cell Membrane‐Anchoring Nano‐Photosensitizer for Light‐Controlled Calcium‐Overload and Tumor‐Specific Synergistic Therapy

M Gao, T Yang, W Qin, Q Wang, M Huang, H Peng… - Small, 2022 - Wiley Online Library
Poor selectivity and unintended toxicity to normal organs are major challenges in calcium
ion (Ca2+) overload tumor therapy. To address this issue, a cell membrane‐anchoring nano …

Bone marrow/bone pre-metastatic niche for breast cancer cells colonization: The role of mesenchymal stromal cells

MC Sanmartin, FR Borzone, MB Giorello… - Critical reviews in …, 2021 - Elsevier
Breast cancer is one of the most common oncological pathologies in women worldwide.
While its early diagnosis has considerably improved, about 70% of advanced patients …

Acid microenvironment in bone sarcomas

G Di Pompo, M Cortini, N Baldini, S Avnet - Cancers, 2021 - mdpi.com
Simple Summary Although rare, malignant bone sarcomas have devastating clinical
implications for the health and survival of young adults and children. To date, efforts to …

Identifying MMP14 and COL12A1 as a potential combination of prognostic biomarkers in pancreatic ductal adenocarcinoma using integrated bioinformatics analysis

J Ding, Y Liu, Y Lai - PeerJ, 2020 - peerj.com
Background Pancreatic ductal adenocarcinoma (PDAC) is a fatal malignant neoplasm. It is
necessary to improve the understanding of the underlying molecular mechanisms and …

Role of αVβ3 in prostate cancer: Metastasis initiator and important therapeutic target

L Tang, M Xu, L Zhang, L Qu, X Liu - OncoTargets and therapy, 2020 - Taylor & Francis
In prostate cancer, distant organ metastasis is the leading cause of patient death. Although
the mechanism of malignant tumor metastasis is unclear, studies have confirmed that …

Chemokines network in bone metastasis: Vital regulators of seeding and soiling

G Sharma, R Pothuraju, RK Kanchan, SK Batra… - Seminars in cancer …, 2022 - Elsevier
Chemokines are well equipped with chemo-attractive signals that can regulate cancer cell
trafficking to specific organ sites. Currently, updated concepts have revealed the diverse role …

Relevance of membrane contact sites in cancer progression

A Gil-Hernández, M Arroyo-Campuzano… - Frontiers in Cell and …, 2021 - frontiersin.org
Membrane contact sites (MCS) are typically defined as areas of proximity between
heterologous or homologous membranes characterized by specific proteins. The study of …