During embryonic development, tissues undergo major rearrangements that lead to germ
layer positioning, patterning, and organ morphogenesis. Often these morphogenetic …

Cell movements are essential for animal development and homeostasis but also contribute
to disease. Moving cells typically extend protrusions towards a chemoattractant, adhere to …

The Hippo pathway regulates organ size and tumorigenesis in Drosophila and mammals
and is altered in a variety of human cancers, yet it remains unclear if the Hippo pathway is of …

Understanding how molecular dynamics leads to cellular behaviours that ultimately sculpt
organs and tissues is a major challenge not only in basic developmental biology but also in …

Oogenesis is a complex developmental process that involves spatiotemporally regulated
coordination between the germline and supporting, somatic cell populations. This process …

The Drosophila melanogaster ovary has served as a popular and successful model for
understanding a wide range of biological processes: stem cell function, germ cell …

N6-methyladenosine is a nonediting RNA modification found in mRNA of all eukaryotes,
from yeast to humans. Although the functional significance of N6-methyladenosine is …

The fruit fly, Drosophila melanogaster, has been used to understand fundamental principles
of genetics and biology for over a century. Drosophila is now also considered an essential …

Morphogenesis of the respiratory appendages on eggshells of Drosophila species provides
a powerful experimental system for studying how cell sheets give rise to complex three …

Organ function relies on the spatial organization and functional coordination of numerous
cell types. The Drosophila ovary is a widely used model system to study the cellular activities …