The COVID-19 pandemic now totaling 13,000,000 cases and over 571,000 deaths has
continued to teach the medical, scientific and lay communities about viral infectious disease …

The association between inflammation, infection, and venous thrombosis has long been
recognized; yet, only in the last decades have we begun to understand the mechanisms …

Lymphoedema is the swelling of one or several parts of the body owing to lymph
accumulation in the extracellular space. It is often chronic, worsens if untreated, predisposes …

COVID-19 patients have a high incidence of thrombosis, and thromboembolic complications
are associated with severe COVID-19 and high mortality. COVID-19 disease is associated …

Sepsis is a multifactorial syndrome primarily determined by the host response to an invading
pathogen. It is common, with over 48 million cases worldwide in 2017, and often lethal. The …

Venous thrombosis (VT) is a common vascular disease associated with reduced survival
and a high recurrence rate. VT is initiated by the accumulation of platelets and neutrophils at …

The Coronavirus Disease 2019 (COVID-19) caused by Severe Acute Respiratory Syndrome
Coronavirus 2 (SARS-CoV-2) and its sublineages pose a new challenge to healthcare …

Platelets are essential for the formation of a haemostatic plug to prevent bleeding, while
neutrophils are the guardians of our immune defences against invading pathogens. The …

Deep vein thrombosis (DVT) and its consequences are lethal, but current models cannot
completely dissect its determinants—endothelium, flow, and blood constituents—together …

BACKGROUND: Cardiac valve disease is observed in 2.5% of the general population and
10% of the elderly people. Effective pharmacological treatments are currently not available …