European Society of Cardiology: cardiovascular disease statistics 2021

A Timmis, P Vardas, N Townsend… - European heart …, 2022 - academic.oup.com
Aims This report from the European Society of Cardiology (ESC) Atlas Project updates and
expands upon the widely cited 2019 report in presenting cardiovascular disease (CVD) …

Global epidemiology, health burden and effective interventions for elevated blood pressure and hypertension

B Zhou, P Perel, GA Mensah, M Ezzati - Nature Reviews Cardiology, 2021 - nature.com
High blood pressure is one of the most important risk factors for ischaemic heart disease,
stroke, other cardiovascular diseases, chronic kidney disease and dementia. Mean blood …

[HTML][HTML] Zilebesiran, an RNA interference therapeutic agent for hypertension

AS Desai, DJ Webb, J Taubel, S Casey… - … England Journal of …, 2023 - Mass Medical Soc
Background Angiotensinogen is the sole precursor of angiotensin peptides and has a key
role in the pathogenesis of hypertension. Zilebesiran, an investigational RNA interference …

Global epidemiology of dyslipidaemias

A Pirillo, M Casula, E Olmastroni, GD Norata… - Nature Reviews …, 2021 - nature.com
Dyslipidaemias are alterations to the plasma lipid profile that are often associated with
clinical conditions. Dyslipidaemias, particularly elevated plasma LDL-cholesterol levels, are …

Role of inflammation, immunity, and oxidative stress in hypertension: New insights and potential therapeutic targets

Z Zhang, L Zhao, X Zhou, X Meng, X Zhou - Frontiers in immunology, 2023 - frontiersin.org
Hypertension is regarded as the most prominent risk factor for cardiovascular diseases,
which have become a primary cause of death, and recent research has demonstrated that …

Nitric oxide signalling in kidney regulation and cardiometabolic health

M Carlström - Nature reviews nephrology, 2021 - nature.com
The prevalence of cardiovascular and metabolic disease coupled with kidney dysfunction is
increasing worldwide. This triad of disorders is associated with considerable morbidity and …

Global prevalence of hypertension in children: a systematic review and meta-analysis

P Song, Y Zhang, J Yu, M Zha, Y Zhu, K Rahimi… - JAMA …, 2019 - jamanetwork.com
Importance Reliable estimates of the prevalence of childhood hypertension serve as the
basis for adequate prevention and treatment. However, the prevalence of childhood …

Adherence to single-pill versus free-equivalent combination therapy in hypertension: a systematic review and meta-analysis

G Parati, S Kjeldsen, A Coca, WC Cushman… - Hypertension, 2021 - Am Heart Assoc
Poor adherence to antihypertensive therapy is a major cause of poor blood pressure (BP)
control in patients with hypertension. Regimen simplification may improve adherence and …

Long-term and recent trends in hypertension awareness, treatment, and control in 12 high-income countries: an analysis of 123 nationally representative surveys

B Zhou, G Danaei, GA Stevens, H Bixby, C Taddei… - The Lancet, 2019 - thelancet.com
Background Antihypertensive medicines are effective in reducing adverse cardiovascular
events. Our aim was to compare hypertension awareness, treatment, and control, and how …

Worldwide trends in blood pressure from 1975 to 2015: a pooled analysis of 1479 population-based measurement studies with 19· 1 million participants

B Zhou, J Bentham, M Di Cesare, H Bixby, G Danaei… - The Lancet, 2017 - thelancet.com
Background Raised blood pressure is an important risk factor for cardiovascular diseases
and chronic kidney disease. We estimated worldwide trends in mean systolic and mean …