Muscle fatigue is a common complaint in clinical practice. In humans, muscle fatigue can be
defined as exercise-induced decrease in the ability to produce force. Here, to provide a …

Intestinal macrophages play a key role in the gut immune system and the regulation of
gastrointestinal physiology, including gut motility and secretion. Their ability to keep the gut …

Nitric oxide (NO) plays important roles in gastrointestinal mucosal defence, as well as in the
pathogenesis of several gastrointestinal diseases (eg irritable bowel syndrome and …

The cellular and systemic effects induced by bacterial lipopolysaccharides (LPS) have been
solely attributed to the activation of the Toll-like receptor 4 (TLR4) signalling cascade …

Mechanosensation is essential for normal gastrointestinal (GI) function, and abnormalities in
mechanosensation are associated with GI disorders. There are several mechanosensitive …

В современной концепции патогенеза синдрома раздраженного кишечника (СРК)
центральная роль отводится расстройству взаимодействия по оси «мозг-кишечник» …

Background and Purpose The transient receptor potential vanilloid 4 (TRPV4) channel is a
non‐selective cation channel involved in physical sensing in various tissue types. The …

Background Abdominal pain in irritable bowel syndrome (IBS) remains challenging to treat
effectively. Researchers have attempted to elucidate visceral nociceptive processes in order …

Ethnopharmacological relevance Asthma is a chronic airway inflammatory disease. Current
treatment of mainstream medications has significant side effects. There is growing evidence …

NAFLD is a clinically progressive disease with steatosis, inflammation, endothelial
dysfunction and fibrosis being the stages where clinical intervention becomes necessary …