Biomimetic design strategies for biomedical applications

X Wei, Y Wang, Y Liu, K Ji, K Li, J Wang, Z Gu - Matter, 2024 - cell.com
Creatures in nature adapt to changing environments by shaping their structures and
functions in ingenious ways. A major focus of current biomedical research is seeking …

Opportunities and challenges of RiPP-based therapeutics

IPM Pfeiffer, MP Schröder, S Mordhorst - Natural Product Reports, 2024 - pubs.rsc.org
Covering: up to 2024Ribosomally synthesised and post-translationally modified peptides
(RiPPs) comprise a substantial group of peptide natural products exhibiting noteworthy …

A wearable osmotic microneedle patch provides high-capacity sustained drug delivery in animal models

S Zhao, Z Lu, R Cai, H Wang, S Gao, C Yang… - Science Translational …, 2024 - science.org
The maintenance of stable plasma drug concentrations within a therapeutic window can be
critical for drug efficacy. Here, we developed a wearable osmotic microneedle (OMN) patch …

A bio-inspired Janus hydrogel patch facilitates oral ulcer repair by combining prolonged wet adhesion and lubrication

Y Zhang, L Liu, X Yu, H Rong, W Chen, J Zhang… - Acta Biomaterialia, 2024 - Elsevier
Oral ulcers, the most common type of mucosal lesion, are both highly prevalent and prone to
recurrence. In the persistently moist environment of the oral cavity, current therapeutic …

Untethered shape-changing devices in the gastrointestinal tract

W Liu, SJ Choi, D George, L Li, Z Zhong… - Expert Opinion on …, 2023 - Taylor & Francis
Introduction Advances in microfabrication, automation, and computer engineering seek to
revolutionize small-scale devices and machines. Emerging trends in medicine point to smart …

Super‐adaptive electroactive programmable adhesive materials to challenging surfaces: From intelligent soft robotics to XR haptic interfaces

SH Jeon, GW Hwang, J Kim, D Lim, Y Son, TH Yang… - InfoMat, 2024 - Wiley Online Library
Recently, the intelligent strategies for adapting to multiple challengeable surfaces of
electroactive programmable materials integrated with bio‐inspired architectures offer …

Natural endogenous material-based vehicles for delivery of macromolecular drugs

LU An, DU Kang, W Meng, ZHU Zehang, LEI Lei… - Chinese Journal of …, 2024 - Elsevier
Natural endogenous materials (NEMs), such as cell and cell derivatives, polysaccharide,
protein and peptide, and nucleic acid-derived vectors, often exhibit biocompatibility …

[HTML][HTML] Oral administration microrobots for drug delivery

A Ren, J Hu, C Qin, N Xia, M Yu, X Xu, H Yang, M Han… - Bioactive Materials, 2024 - Elsevier
Oral administration is the most simple, noninvasive, convenient treatment. With the
increasing demands on the targeted drug delivery, the traditional oral treatment now is …

Trends in Photopolymerization 3D Printing for Advanced Drug Delivery Applications

Y Hu, Z Luo, Y Bao - Biomacromolecules, 2024 - ACS Publications
Since its invention in the 1980s, photopolymerization-based 3D printing has attracted
significant attention for its capability to fabricate complex microstructures with high precision …

Enhancing Buccal Drug Delivery: The Impact of Glycerol in Slot-Die-Coated Pectin Films

E Pantazoglou, M Tollemeto, NZ Ezazi… - Molecular …, 2024 - ACS Publications
Buccal delivery offers a promising alternative to eg, oral or parenteral drug administrations
by leveraging the mucosal membranes of the mouth to enhance drug absorption and …