Animal models for COVID-19: advances, gaps and perspectives

C Fan, Y Wu, X Rui, Y Yang, C Ling, S Liu… - Signal transduction and …, 2022 - nature.com
Abstract COVID-19, caused by SARS-CoV-2, is the most consequential pandemic of this
century. Since the outbreak in late 2019, animal models have been playing crucial roles in …

[HTML][HTML] Antigenic evolution of SARS coronavirus 2

AZ Mykytyn, RAM Fouchier, BL Haagmans - Current Opinion in Virology, 2023 - Elsevier
SARS coronavirus 2 (SARS-CoV-2), the causative agent of COVID-19, emerged in China in
December 2019. Vaccines developed were very effective initially, however, the virus has …

[HTML][HTML] TMEM106B is a receptor mediating ACE2-independent SARS-CoV-2 cell entry

J Baggen, M Jacquemyn, L Persoons, E Vanstreels… - Cell, 2023 - cell.com
SARS-CoV-2 is associated with broad tissue tropism, a characteristic often determined by
the availability of entry receptors on host cells. Here, we show that TMEM106B, a lysosomal …

Global landscape of SARS-CoV-2 mutations and conserved regions

MH Abbasian, M Mahmanzar, K Rahimian… - Journal of Translational …, 2023 - Springer
Background At the end of December 2019, a novel strain of Severe Acute Respiratory
Syndrome Coronavirus 2 (SARS-CoV-2) disease (COVID-19) has been identified in Wuhan …

SARS‐CoV‐2 papain‐like protease: structure, function and inhibition

S Ullrich, C Nitsche - Chembiochem, 2022 - Wiley Online Library
Emerging variants of SARS‐CoV‐2 and potential novel epidemic coronaviruses underline
the importance of investigating various viral proteins as potential drug targets. The papain …

Innate and adaptive immunity during SARS-CoV-2 infection: biomolecular cellular markers and mechanisms

B Brown, V Ojha, I Fricke, SA Al-Sheboul, C Imarogbe… - Vaccines, 2023 - mdpi.com
The coronavirus 2019 (COVID-19) pandemic was caused by a positive sense single-
stranded RNA (ssRNA) severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) …

Beyond COVID-19: Do biothermodynamic properties allow predicting the future evolution of SARS-CoV-2 variants?

M Popovic - Microbial risk analysis, 2022 - Elsevier
During the COVID-19 pandemic, many statistical and epidemiological studies have been
published, trying to predict the future development of the SARS-CoV-2 pandemic. However …

From alpha to omicron: how different variants of concern of the SARS-Coronavirus-2 impacted the world

M Andre, LS Lau, MD Pokharel, J Ramelow, F Owens… - Biology, 2023 - mdpi.com
Simple Summary This review article comprehensively discussed the evolution of the SARS-
CoV-2 virus since its initial outbreak in 2019. Specifically, we have provided insights into the …

Deciphering the relationship between SARS-CoV-2 and cancer

M Costanzo, MAR De Giglio, GN Roviello - International Journal of …, 2023 - mdpi.com
Some viruses are known to be associated with the onset of specific cancers. These
microorganisms, oncogenic viruses or oncoviruses, can convert normal cells into cancer …

SARS-CoV-2 ORF8: a rapidly evolving immune and viral modulator in COVID-19

A Arduini, F Laprise, C Liang - Viruses, 2023 - mdpi.com
The COVID-19 pandemic has resulted in upwards of 6.8 million deaths over the past three
years, and the frequent emergence of variants continues to strain global health. Although …