Polymeric micelles for the delivery of poorly soluble drugs: From nanoformulation to clinical approval
Over the last three decades, polymeric micelles have emerged as a highly promising drug
delivery platform for therapeutic compounds. Particularly, poorly soluble small molecules …
delivery platform for therapeutic compounds. Particularly, poorly soluble small molecules …
Nanogels: An overview of properties, biomedical applications and obstacles to clinical translation
Nanogels have emerged as a versatile hydrophilic platform for encapsulation of guest
molecules with a capability to respond to external stimuli that can be used for a multitude of …
molecules with a capability to respond to external stimuli that can be used for a multitude of …
Recent advances in nanoparticle-based cancer drug and gene delivery
Effective and safe delivery of anticancer agents is among the major challenges in cancer
therapy. The majority of anticancer agents are toxic to normal cells, have poor bioavailability …
therapy. The majority of anticancer agents are toxic to normal cells, have poor bioavailability …
Biomedical, clinical and environmental applications of platinum-based nanohybrids: An updated review
Abstract Platinum nanoparticles (Pt NPs) have numerous applications in various sectors,
including pharmacology, nanomedicine, cancer therapy, radiotherapy, biotechnology and …
including pharmacology, nanomedicine, cancer therapy, radiotherapy, biotechnology and …
Nanogels for delivery, imaging and therapy
AJ Sivaram, P Rajitha, S Maya… - Wiley …, 2015 - Wiley Online Library
Nanogels are hydrogels having size in nanoregime, which is composed of cross‐linked
polymer networks. The advantages of nanogels include stimuli‐responsive nature, easy …
polymer networks. The advantages of nanogels include stimuli‐responsive nature, easy …
Can nanomedicines kill cancer stem cells?
Most tumors are heterogeneous and many cancers contain small population of highly
tumorigenic and intrinsically drug resistant cancer stem cells (CSCs). Like normal stem cell …
tumorigenic and intrinsically drug resistant cancer stem cells (CSCs). Like normal stem cell …
Targeted delivery of cisplatin by LHRH-peptide conjugated dextran nanoparticles suppresses breast cancer growth and metastasis
The metastasis of breast cancer is the leading cause of cancer death in women. In this work,
an attempt to simultaneously inhibit the primary tumor growth and organ-specific metastasis …
an attempt to simultaneously inhibit the primary tumor growth and organ-specific metastasis …
LHRH conjugated gold nanoparticles assisted efficient ovarian cancer targeting evaluated via spectral photon-counting CT imaging: a proof-of-concept research
D Kumar, M Moghiseh, K Chitcholtan… - Journal of Materials …, 2023 - pubs.rsc.org
Emerging multifunctional nanoparticulate formulations take advantage of nano-meter scale
size and surface chemistry to work as a therapeutic delivery agent and a diagnostic tool for …
size and surface chemistry to work as a therapeutic delivery agent and a diagnostic tool for …
Decapeptide functionalized targeted mesoporous silica nanoparticles with doxorubicin exhibit enhanced apoptotic effect in breast and prostate cancer cells
Background Considering the increase in cancer cases and number of deaths per year
worldwide, development of potential therapeutics is imperative. Mesoporous silica …
worldwide, development of potential therapeutics is imperative. Mesoporous silica …
Polymeric biomaterials for the delivery of platinum-based anticancer drugs
Since cisplatin, cis-diamminedichloroplatinum (II), received FDA approval for use in cancer
treatment in 1978, platinum-based drugs have been one of the most widely used drugs for …
treatment in 1978, platinum-based drugs have been one of the most widely used drugs for …