Early involvement of gut is observed in Parkinson's disease (PD) and symptoms such as
constipation may precede motor symptoms. α-Synuclein pathology is extensively evident in …

Background Parkinson's disease (PD) is a neurodegenerative disorder characterized by a
combination of motor and non-motor dysfunction. Dysphagia is a common symptom in PD …

Introduction Neurogenic dysphagia defines swallowing disorders caused by diseases of the
central and peripheral nervous system, neuromuscular transmission, or muscles …

Abstract Background Pharyngeal dysphagia in Parkinson's disease (PD) is a common and
clinically relevant symptom associated with poor nutrition intake, reduced quality of life, and …

High-resolution manometry has traditionally been utilized in gastroenterology diagnostic
clinical and research applications. Recently, it is also finding new and important applications …

Mutations in the RNA-binding protein (RBP) FUS have been genetically associated with the
motoneuron disease amyotrophic lateral sclerosis (ALS). Using both human induced …

Screening tests and clinical swallow examination should be routinely performed in
neurological patients at risk for dysphagia. In patients testing positive for dysphagia, first-line …

Dysphagia is a highly prevalent disorder in Parkinson's Disease (PD) characterized by
changes in swallowing kinematics, residue, and airway invasion. These changes can lead to …

Purpose Swallowing impairment, or dysphagia, is a known contributor to reduced quality of
life, pneumonia, and mortality in Parkinson's disease (PD). However, the contribution of …

Dysphagia is a common symptom that is important to recognise and appropriately manage,
given that causes include life threatening oesophageal neoplasia, oropharyngeal …