Protein misfolding and aggregation is observed in many amyloidogenic diseases affecting
either the central nervous system or a variety of peripheral tissues. Structural and dynamic …

Neurodegenerative diseases pose a substantial socioeconomic burden on society.
Unfortunately, the aging world population and lack of effective cures foreshadow a negative …

Amyotrophic lateral sclerosis (ALS), also known as Lou Gehrig's disease or Charcot
disease, is a fatal neurodegenerative disease that affects motor neurons (MNs) and leads to …

Free radicals are formed as a part of normal metabolic activities but are neutralized by the
endogenous antioxidants present in cells/tissue, thus maintaining the redox balance. This …

Background: Despite the extensive research in recent years, the current treatment modalities
for neurological disorders are suboptimal. Curcumin, a polyphenol majorly found in …

Copper is an essential trace element for the human body since it is a cofactor of several
enzymes and proteins and plays a pivotal role in several biological functions (eg …

The objective of present study was to assess the safety and efficacy of nanocurcumin as an
anti-inflammatory and antioxidant agent in adults with amyotrophic lateral sclerosis (ALS) …

Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease that produces a
selective loss of the motor neurons of the spinal cord, brain stem and motor cortex. Oxidative …

Herein, we show differences in blood serum of asymptomatic and symptomatic pregnant
women infected with COVID-19 and correlate them with laboratory indexes, ATR FTIR and …

Aberrant protein folding known as protein misfolding is counted as one of the striking factors
of neurodegenerative diseases. The extensive range of pathologies caused by protein …