Brain-gut-microbiota axis and mental health

TG Dinan, JF Cryan - Psychosomatic medicine, 2017 - journals.lww.com
Objective The brain-gut-microbiota axis has been put forward as a new paradigm in
neuroscience, which may be of relevance to mental illness. The mechanisms of signal …

Beyond the association. Toxoplasma gondii in schizophrenia, bipolar disorder, and addiction: systematic review and meta‐analysis

AL Sutterland, G Fond, A Kuin… - Acta Psychiatrica …, 2015 - Wiley Online Library
Objective To perform a meta‐analysis on studies reporting prevalence of T oxoplasma
gondii (T. gondii) infection in any psychiatric disorder compared with healthy controls. Our …

May the force be with you: the light and dark sides of the microbiota–gut–brain axis in neuropsychiatry

E Sherwin, KV Sandhu, TG Dinan, JF Cryan - CNS drugs, 2016 - Springer
The role of the gut microbiota in health and disease is becoming increasingly recognized.
The microbiota–gut–brain axis is a bi-directional pathway between the brain and the …

Cross talk: the microbiota and neurodevelopmental disorders

JR Kelly, C Minuto, JF Cryan, G Clarke… - Frontiers in …, 2017 - frontiersin.org
Humans evolved within a microbial ecosystem resulting in an interlinked physiology. The gut
microbiota can signal to the brain via the immune system, the vagus nerve or other host …

Microbiota regulation of the mammalian gut–brain axis

A Burokas, RD Moloney, TG Dinan, JF Cryan - Advances in applied …, 2015 - Elsevier
The realization that the microbiota–gut–brain axis plays a critical role in health and disease
has emerged over the past decade. The brain–gut axis is a bidirectional communication …

Inflammation and the two-hit hypothesis of schizophrenia

KA Feigenson, AW Kusnecov, SM Silverstein - … & Biobehavioral Reviews, 2014 - Elsevier
The high societal and individual cost of schizophrenia necessitates finding better, more
effective treatment, diagnosis, and prevention strategies. One of the obstacles in this …

Immune aging, dysmetabolism, and inflammation in neurological diseases

M Deleidi, M Jäggle, G Rubino - Frontiers in neuroscience, 2015 - frontiersin.org
As we age, the immune system undergoes a process of senescence accompanied by the
increased production of proinflammatory cytokines, a chronic subclinical condition named as …

Genomics of schizophrenia: time to consider the gut microbiome?

TG Dinan, YE Borre, JF Cryan - Molecular psychiatry, 2014 - nature.com
Research into the genomics of schizophrenia promises much, but so far is resplendent with
failures to replicate, and has yielded little of therapeutic potential. Within our bodies resides …

[HTML][HTML] The role of the gut microbiome in the development of schizophrenia

JR Kelly, C Minuto, JF Cryan, G Clarke… - Schizophrenia Research, 2021 - Elsevier
Schizophrenia is a heterogeneous neurodevelopmental disorder involving the convergence
of a complex and dynamic bidirectional interaction of genetic expression and the …

Strain hypothesis of Toxoplasma gondii infection on the outcome of human diseases

J Xiao, RH Yolken - Acta physiologica, 2015 - Wiley Online Library
The intracellular protozoan Toxoplasma gondii is an exceptionally successful food and
waterborne parasite that infects approximately 1 billion people worldwide. Genotyping of T …