Multi-omics research in sarcopenia: current progress and future prospects

JC Liu, SS Dong, H Shen, DY Yang, BB Chen… - Ageing Research …, 2022 - Elsevier
Sarcopenia is a systemic disease with progressive and generalized skeletal muscle
dysfunction defined by age-related low muscle mass, high content of muscle slow fibers, and …

Screening for Sarcopenia (Physical Frailty) in the COVID‐19 Era

AM Ali, H Kunugi - International journal of endocrinology, 2021 - Wiley Online Library
Although the numbers of aged populations have risen considerably in the last few decades,
the current coronavirus disease 2019 (COVID‐19) has revealed an extensive vulnerability …

The contribution of diet therapy and probiotics in the treatment of sarcopenia induced by prolonged immobilization caused by the COVID-19 pandemic

CD Nistor-Cseppento, TD Moga, AF Bungau, DM Tit… - Nutrients, 2022 - mdpi.com
The prolonged immobilization associated with COVID-19 infection and the restrictions
imposed by the pandemic have determined major changes in physical activity and eating …

Unveiling genetic variants for age-related sarcopenia by conducting a genome-wide association study on Korean cohorts

H Jin, HJ Yoo, YA Kim, JH Lee, Y Lee, S Kwon… - Scientific Reports, 2022 - nature.com
Sarcopenia is an age-related disorder characterised by a progressive decrease in skeletal
muscle mass. As the genetic biomarkers for sarcopenia are not yet well characterised, this …

Sarcopenia, obesity, and sarcopenic obesity: Relationship with skeletal muscle phenotypes and single nucleotide polymorphisms

P Khanal, AG Williams, L He, GK Stebbings… - Journal of Clinical …, 2021 - mdpi.com
Obesity may aggravate the effects of sarcopenia on skeletal muscle structure and function in
the elderly, but no study has attempted to identify the gene variants associated with …

Static one-leg standing balance test as a screening tool for low muscle mass in healthy elderly women

P Khanal, L He, GK Stebbings… - Aging clinical and …, 2021 - Springer
Background Identification of simple screening tools for detecting lower skeletal muscle mass
may be beneficial for planning effective interventions in the elderly. Aims We aimed to (1) …

The association of multiple gene variants with ageing skeletal muscle phenotypes in elderly women

P Khanal, L He, AJ Herbert, GK Stebbings… - Genes, 2020 - mdpi.com
There is a scarcity of studies that have investigated the role of multiple single nucleotide
polymorphisms (SNPs) on a range of muscle phenotypes in an elderly population. The …

Genetic profile of sports climbing athletes from three different ethnicities

M Saito, M Ginszt, E Semenova, M Massidda… - Biology of …, 2022 - termedia.pl
This study aimed to investigate the ACTN3 R577X, ACE I/D, CKM rs8111989, and TRHR
rs7832552 genotypes in climbers and controls in three ethnicities. The study consisted of …

Genetic polymorphisms of muscular fitness in young healthy men

T Venckunas, H Degens - Plos one, 2022 - journals.plos.org
The effects of genetic polymorphisms on muscle structure and function remain elusive. The
present study tested for possible associations of 16 polymorphisms (across ten candidate …

Immunogenetic aspects of sarcopenic obesity

Ł Mazurkiewicz, K Czernikiewicz, B Grygiel-Górniak - Genes, 2024 - mdpi.com
Sarcopenic obesity (SO) is a combination of obesity and sarcopenia, with diagnostic criteria
defined as impaired skeletal muscle function and altered body composition (eg, increased …