Shaping magnetic fields to direct therapy to ears and eyes

B Shapiro, S Kulkarni, A Nacev, A Sarwar… - Annual review of …, 2014 - annualreviews.org
Magnetic fields have the potential to noninvasively direct and focus therapy to disease
targets. External magnets can apply forces on drug-coated magnetic nanoparticles, or on …

The behaviors of ferromagnetic nano-particles in and around blood vessels under applied magnetic fields

A Nacev, C Beni, O Bruno, B Shapiro - Journal of magnetism and magnetic …, 2011 - Elsevier
In magnetic drug delivery, therapeutic magnetizable particles are typically injected into the
blood stream and magnets are then used to concentrate them to disease locations. The …

The difference in ventilation heterogeneity between asthmatic and healthy subjects quantified using hyperpolarized 3He MRI

YS Tzeng, K Lutchen, M Albert - Journal of applied …, 2009 - journals.physiology.org
In this pilot study, algorithms for quantitatively evaluating the distribution and heterogeneity
of human ventilation imaged with hyperpolarized (HP) 3He MRI were developed for the goal …

Towards control of magnetic fluids in patients: directing therapeutic nanoparticles to disease locations

A Nacev, A Komaee, A Sarwar, R Probst… - IEEE Control …, 2012 - ieeexplore.ieee.org
This article describes a range of results, from passive magnet design to optimal feedback
control of a distributed ferrofluid. Representing magnetic forces as the gradient of a magnetic …

In vivo imaging of carbon nanotube biodistribution using magnetic resonance imaging

A Al Faraj, K Cieslar, G Lacroix, S Gaillard… - Nano Letters, 2009 - ACS Publications
As novel engineered nanoparticles such as carbon nanotubes (CNTs) are extensively used
in nanotechnology due to their superior properties, it becomes critical to fully understand …

An open-access, very-low-field MRI system for posture-dependent 3He human lung imaging

LL Tsai, RW Mair, MS Rosen, S Patz… - Journal of Magnetic …, 2008 - Elsevier
We describe the design and operation of an open-access, very-low-field, magnetic
resonance imaging (MRI) system for in vivo hyperpolarized 3He imaging of the human …

[HTML][HTML] A two-magnet system to push therapeutic nanoparticles

B Shapiro, K Dormer, IB Rutel - AIP conference proceedings, 2010 - ncbi.nlm.nih.gov
Magnetic fields can be used to direct magnetically susceptible nanoparticles to disease
locations: to infections, blood clots, or tumors. Any single magnet always attracts (pulls) ferro …

Quantitative MRI evaluation of Ferritin overexpression in non-small-cell lung cancer

M Singhania, A Zaher, CF Pulliam… - International journal of …, 2024 - mdpi.com
Cancer cells frequently present elevated intracellular iron levels, which are thought to
facilitate an enhanced proliferative capacity. Targeting iron metabolism within cancer cells …

Magnetic resonance methods and applications in pharmaceutical research

I Rodríguez, S Pérez-Rial, J González-Jimenez… - Journal of …, 2008 - Elsevier
This review presents an overview of some recent magnetic resonance (MR) techniques for
pharmaceutical research. MR is noninvasive, and does not expose subjects to ionizing …

Enhanced 129Xe T1 relaxation in whole blood and in the presence of SPIONs at low magnetic field strengths

N Bryden, SW Atalla, M Kelley… - Magnetic …, 2023 - Wiley Online Library
Purpose To compare the effect of superparamagnetic iron oxide nanoparticles (SPIONs) on
the T 1 of 129Xe and 1H and to measure the relaxation of 129Xe in blood at low and high …