The use of natural compounds is promising in approaches to prevent and treat cancer. The
long-term application of most currently employed chemotherapy techniques has toxic side …

Background Eugenol is a natural phenolic compound and possesses anticancer and
antibacterial activities. Breast cancer is a major global health problem, and most of the …

Inhibitor of differentiation (ID) proteins are key regulators of development and tumorigenesis.
One member of this family, ID4, controls lineage commitment during mammary gland …

Background Breast cancer is affected by the immune system in that different cytokines play
roles in its initiation and progression. Interleukin-10 (IL-10), an anti-inflammatory cytokine, is …

Genetic analysis on formalin‐fixed paraffin‐embedded (FFPE) tissue specimens has
become a mainstream method, from conventional direct sequencing to comprehensive …

The aberrant hypermethylation of BRCA1 promoter CpG islands induces the decreased
expression of BRCA1 (Breast Cancer 1) protein. It can be detected in sporadic breast cancer …

Cathepsin S (CTSS) is a cysteine protease that is thought to play a role in many
physiological and pathological processes including tumor growth, angiogenesis, and …

BRCA1 plays a suppressive role in breast tumorigenesis. Ubiquitin-dependent degradation
is a common mechanism that regulates BRCA1 protein stability, and several ubiquitin …

Background Apoptosis or programmed cell death plays a vital role in maintaining
homeostasis and, therefore, is a tightly regulated process. Deregulation of apoptosis …

Abstract Introduction MicroRNAs (MIRs) play a crucial role in colorectal cancer (CRC)
development and metastasis by regulating immune responses. Tumour-infiltrating …