Recent advances in research for potential utilization of unexplored lichen metabolites

R Kalra, XA Conlan, M Goel - Biotechnology Advances, 2023 - Elsevier
Several research studies have shown that lichens are productive organisms for the
synthesis of a broad range of secondary metabolites. Lichens are a self-sustainable stable …

Discovery and excavation of lichen bioactive natural products

M Ren, S Jiang, Y Wang, X Pan, F Pan… - Frontiers in …, 2023 - frontiersin.org
Lichen natural products are a tremendous source of new bioactive chemical entities for drug
discovery. The ability to survive in harsh conditions can be directly correlated with the …

Putative identification of the usnic acid biosynthetic gene cluster by de novo whole-genome sequencing of a lichen-forming fungus

M Abdel-Hameed, RL Bertrand, MD Piercey-Normore… - Fungal biology, 2016 - Elsevier
To identify the biosynthetic gene cluster responsible for the biosynthesis of the polyketide
usnic acid we carried out the de novo genome sequencing of the fungal partner of Cladonia …

Lichen biosynthetic gene clusters. Part I. Genome sequencing reveals a rich biosynthetic potential

RL Bertrand, M Abdel-Hameed… - Journal of natural …, 2018 - ACS Publications
Lichens are symbionts of fungi and algae that produce diverse secondary metabolites with
useful properties. Little is known of lichen natural product biosynthesis because of the …

Enhanced culturing techniques for the mycobiont isolated from the lichen Xanthoria parietina

G Pichler, F Candotto Carniel, L Muggia… - Mycological …, 2021 - Springer
Lichens and their isolated symbionts are potentially valuable resources for biotechnological
approaches. Especially mycobiont cultures that produce secondary lichen products are …

A comprehensive catalogue of polyketide synthase gene clusters in lichenizing fungi

RL Bertrand, JL Sorensen - Journal of Industrial Microbiology …, 2018 - academic.oup.com
Lichens are fungi that form symbiotic partnerships with algae. Although lichens produce
diverse polyketides, difficulties in establishing and maintaining lichen cultures have …

Stressed out: the effects of heat stress and parasitism on gene expression of the lichen-forming fungus Lobaria pulmonaria

M Kraft, C Scheidegger, S Werth - The Lichenologist, 2022 - cambridge.org
Gene expression variation can be partitioned into different components (regulatory, genetic
and acclimatory effects) but for lichen-forming fungi, the relative importance of each of these …

A molecular phylogenetic evaluation of the Ramalina siliquosa complex, with notes on species circumscription and relationships within Ramalina

S LaGreca, HT Lumbsch, M Kukwa, X Wei, JE Han… - The …, 2020 - cambridge.org
Lichens of the Ramalina siliquosa complex dominate seashore cliffs in Europe and South-
East Asia, but their taxonomy has been vigorously debated for over a century. On many cliffs …

Development and validation of a reliable LC–MS/MS method for quantitative analysis of usnic acid in Cladonia uncialis

N Sveshnikova, T Yuan, JM Warren… - BMC Research …, 2019 - Springer
Objective The purpose of this study was to develop and validate a specific and sensitive
liquid chromatography tandem mass-spectrometry method for quantification of usnic acid …

Relationship between lichen species composition, secondary metabolites and soil pH, organic matter, and grain characteristics in Manitoba

M Zraik, T Booth, MD Piercey-Normore - Botany, 2018 - cdnsciencepub.com
Many lichen secondary metabolites have functions related to the environmental conditions
of lichen habitats but few studies have compared soil characteristics with lichen species …