Human babesiosis in Europe

A Hildebrandt, A Zintl, E Montero, KP Hunfeld, J Gray - Pathogens, 2021 - mdpi.com
Babesiosis is attracting increasing attention as a worldwide emerging zoonosis. The first
case of human babesiosis in Europe was described in the late 1950s and since then more …

Treatment of human babesiosis: then and now

I Renard, C Ben Mamoun - Pathogens, 2021 - mdpi.com
Babesiosis is an emerging tick-borne disease caused by apicomplexan parasites of the
genus Babesia. With its increasing incidence worldwide and the risk of human-to-human …

Unravelling the pharmacological properties of cryptolepine and its derivatives: a mini-review insight

CK Tudu, A Bandyopadhyay, M Kumar, Radha… - Naunyn-schmiedeberg's …, 2023 - Springer
Abstract Cryptolepine (1, 5-methyl-10 H-indolo [3, 2-b] quinoline), an indoloquinoline
alkaloid, found in the roots of Cryptolepis sanguinolenta (Lindl.) Schltr (family …

[HTML][HTML] Bioactive compounds and their libraries: an insight into prospective phytotherapeutics approach for oral mucocutaneous cancers

HA Adeola, A Bano, R Vats, A Vashishtha… - Biomedicine & …, 2021 - Elsevier
Oral mucocutaneous cancers (OMCs) are cancers that affect both the oral mucosa and
perioral cutaneous structures. Common OMCs are squamous cell carcinoma (SCC), basal …

Identification of novel immune correlates of protection against acute bovine babesiosis by superinfecting cattle with in vitro culture attenuated and virulent Babesia …

RG Bastos, JM Laughery, S Ozubek, HF Alzan… - Frontiers in …, 2022 - frontiersin.org
The apicomplexan tickborne parasites Babesia bovis and B. bigemina are the major
causative agents of bovine babesiosis, a disease that negatively affects the cattle industry …

Botanical medicines Cryptolepis sanguinolenta, Artemisia annua, Scutellaria baicalensis, Polygonum cuspidatum, and Alchornea cordifolia demonstrate inhibitory …

Y Zhang, H Alvarez-Manzo, J Leone… - Frontiers in Cellular …, 2021 - frontiersin.org
Human babesiosis is a CDC reportable disease in the United States and is recognized as
an emerging health risk in multiple parts of the world. The current treatment for human …

Comparison of the Efficacy of Longer versus Shorter Pulsed High Dose Dapsone Combination Therapy in the Treatment of Chronic Lyme Disease/Post Treatment …

RI Horowitz, J Fallon, PR Freeman - Microorganisms, 2023 - mdpi.com
Twenty-five patients with relapsing and remitting Borreliosis, Babesiosis, and bartonellosis
despite extended anti-infective therapy were prescribed double-dose dapsone combination …

Exploring the Nucleobase-Specific Hydrophobic Interaction of Cryptolepine Hydrate with RNA and Its Subsequent Sequestration

A Nandy, S Shekhar, BK Paul, S Mukherjee - Langmuir, 2021 - ACS Publications
The study of the interactions of drug molecules with genetic materials plays a key role
underlying the development of new drugs for many life-threatening diseases in …

[HTML][HTML] Mutant P53 modulation by cryptolepine through cell cycle arrest and apoptosis in triple negative breast cancer

H Qayoom, MA Mir - Biomedicine & Pharmacotherapy, 2024 - Elsevier
Abstract Background Triple Negative Breast cancer is an aggressive breast cancer subtype.
It has a more aggressive clinical course, an earlier age of onset, a larger propensity for …

Cryptolepine Suppresses Colorectal Cancer Cell Proliferation, Stemness, and Metastatic Processes by Inhibiting WNT/β-Catenin Signaling

JT Quarshie, K Fosu, NA Offei, AK Sobo, O Quaye… - Pharmaceuticals, 2023 - mdpi.com
Colorectal cancer (CRC) is the third most frequent cancer and the second leading cause of
cancer-related deaths globally. Evidence shows that over 90% of CRC cases are initiated by …