In human pregnancy, successful placentation and remodelling of the uterine vasculature
require the integration of a number of stages, which are crucial for a healthy pregnancy. As …

Invasion of placental trophoblasts into uterine tissue and vessels is an essential process of
human pregnancy and fetal development. Due to their remarkable plasticity invasive …

A number of important changes take place in the maternal uterine vasculature during the first
few weeks of pregnancy resulting in increased blood flow to the intervillous space. Vascular …

During the first twenty weeks of human pregnancy, extravillous trophoblasts (EVT) colonise
the decidua and remodel the uterine spiral arteries as far as the first third of the myometrium …

Individuals may regard reproduction as optional but sufficient number of them must be
productive to perpetuate the species. The reproductive system is surprisingly vulnerable and …

During the first trimester of pregnancy, the uterine spiral arteries are remodeled, creating
heavily dilated conduits that lack maternal vasomotor control but allow the placenta to meet …

We have used magnetic resonance imaging (MRI) to provide important new insights into the
function of the human placenta in utero. We have measured slow net flow and high net …

During human pregnancy, the uterine spiral arteries are progressively remodelled to form
dilated conduits lacking maternal vasomotor control. This phenomenon ensures that a …

Failure of uterine vascular transformation is associated with pregnancy complications
including Intra Uterine Growth Restriction (IUGR). The decidua and its immune cell …

Hemochorial placentation is characterized by the development of trophoblast cells
specialized to interact with the uterine vascular bed. We utilized trophoblast stem (TS) cell …