M Knöfler - The International journal of developmental biology, 2010 - ncbi.nlm.nih.gov
Invasion of placental trophoblasts into uterine tissue and vessels is an essential process of human pregnancy and fetal development. Due to their remarkable plasticity invasive …
GSJ Whitley, JE Cartwright - Placenta, 2010 - Elsevier
A number of important changes take place in the maternal uterine vasculature during the first few weeks of pregnancy resulting in increased blood flow to the intervillous space. Vascular …
During the first twenty weeks of human pregnancy, extravillous trophoblasts (EVT) colonise the decidua and remodel the uterine spiral arteries as far as the first third of the myometrium …
Individuals may regard reproduction as optional but sufficient number of them must be productive to perpetuate the species. The reproductive system is surprisingly vulnerable and …
LK Harris, SD Smith, RJ Keogh, RL Jones… - The American journal of …, 2010 - Elsevier
During the first trimester of pregnancy, the uterine spiral arteries are remodeled, creating heavily dilated conduits that lack maternal vasomotor control but allow the placenta to meet …
NS Dellschaft, G Hutchinson, S Shah, NW Jones… - PLoS …, 2020 - journals.plos.org
We have used magnetic resonance imaging (MRI) to provide important new insights into the function of the human placenta in utero. We have measured slow net flow and high net …
During human pregnancy, the uterine spiral arteries are progressively remodelled to form dilated conduits lacking maternal vasomotor control. This phenomenon ensures that a …
C Dunk, M Kwan, A Hazan, S Walker… - Frontiers in …, 2019 - frontiersin.org
Failure of uterine vascular transformation is associated with pregnancy complications including Intra Uterine Growth Restriction (IUGR). The decidua and its immune cell …
Hemochorial placentation is characterized by the development of trophoblast cells specialized to interact with the uterine vascular bed. We utilized trophoblast stem (TS) cell …