Panax ginseng and aging related disorders: A systematic review

B de Oliveira Zanuso, ARO Dos Santos… - Experimental …, 2022 - Elsevier
The aging process predisposes numerous homeostatic disorders, metabolic disorders,
cardiovascular diseases, neurodegenerative diseases, and cancer. Changes in diet and …

Piper longum L.: A comprehensive review on traditional uses, phytochemistry, pharmacology, and health‐promoting activities

P Biswas, M Ghorai, T Mishra… - Phytotherapy …, 2022 - Wiley Online Library
Piper longum (family Piperaceae), commonly known as “long‐pepper” or “Pippali” grows as
a perennial shrub or as an herbaceous vine. It is native to the Indo‐Malaya region and …

Resveratrol in rodent models of Parkinson's disease: A systematic review of experimental studies

CF Su, L Jiang, XW Zhang, A Iyaswamy… - Frontiers in …, 2021 - frontiersin.org
Parkinson's disease (PD) is a common neurodegenerative disease featured by progressive
degeneration of nigrostriatal dopaminergic neurons (DA) accompanied with motor function …

Artemisia Leaf Extract protects against neuron toxicity by TRPML1 activation and promoting autophagy/mitophagy clearance in both in vitro and in vivo models of …

LK Wu, S Agarwal, CH Kuo, YL Kung, CH Day, PY Lin… - Phytomedicine, 2022 - Elsevier
Background Parkinson's disease (PD) is a neurodegenerative disorder involving the
degeneration of dopaminergic neurons in the substantia nigra pars compacta (SNpc) …

Brain organoids are new tool for drug screening of neurological diseases

JQ Zhou, LH Zeng, CT Li, DH He… - Neural Regeneration …, 2023 - journals.lww.com
At the level of in vitro drug screening, the development of a phenotypic analysis system with
high-content screening at the core provides a strong platform to support high-throughput …

Network pharmacology-based strategy to investigate the pharmacologic mechanisms of coptidis rhizoma for the treatment of alzheimer's disease

X Ye, H Wang, S Cheng, L Xia, X Xu… - Frontiers in Aging …, 2022 - frontiersin.org
Background Alzheimer's disease (AD) is becoming a more prevalent public health issue in
today's culture. The experimental study of Coptidis Rhizoma (CR) and its chemical …

Qingyangshen mitigates amyloid-β and Tau aggregate defects involving PPARα-TFEB activation in transgenic mice of Alzheimer's disease

A Iyaswamy, SK Krishnamoorthi, H Zhang… - Phytomedicine, 2021 - Elsevier
Background Alzheimer's disease (AD) is the most common neurodegenerative disease.
Deposition of amyloid β plaques (Aβ) and neurofibrillary tangles (NFTs) is the key …

Paeoniflorin is a promising natural monomer for neurodegenerative diseases via modulation of Ca2+ and ROS homeostasis

W Peng, Y Chen, S Tumilty, L Liu, L Luo, H Yin… - Current Opinion in …, 2022 - Elsevier
Neurodegenerative diseases (NDDs) are a range of neurological disorders featured by
neuronal degeneration and apoptosis. Cellular Calcium (Ca 2+) and reactive oxygen …

Neuroprotective effects of naturally sourced bioactive polysaccharides: An update

XL Xu, S Li, R Zhang, WD Le - Neural Regeneration Research, 2022 - journals.lww.com
Polysaccharides are macromolecular complexes that have various biological activities. In
vivo and in vitro studies have shown that polysaccharides play neuroprotective roles through …

Klotho an autophagy stimulator as a potential therapeutic target for Alzheimer's disease: A review

TY Fung, A Iyaswamy, SG Sreenivasmurthy… - Biomedicines, 2022 - mdpi.com
Alzheimer's disease (AD) is an age-associated neurodegenerative disease; it is the most
common cause of senile dementia. Klotho, a single-pass transmembrane protein primarily …