Highlights•Precision medicine is necessary to treat multiple facets of osteoarthritis.•Disease-
modifying osteoarthritis drugs (DMOADs) and drug delivery systems (DDSs) are …

Peptide-and protein-based therapeutics have drawn significant attention over the past few
decades for the treatment of infectious diseases, genetic disorders, oncology, and many …

The global pharmaceutical market has recently shifted its focus from small molecule drugs to
peptide, protein, and nucleic acid drugs, which now comprise a majority of the top-selling …

Despite the beneficial properties and outstanding potential of hydrogels for biomedical
applications, several unmet challenges must be overcome, especially regarding to their …

Lipid nanoparticles (LNPs) have gained prominence as primary carriers for delivering a
diverse array of therapeutic agents. Biological products have achieved a solid presence in …

Usually the topical delivery of ocular drugs poses a great challenge. Accordingly, the work in
this study comprised the use of different hybrids of generally regarded as safe (GRAS) oils …

Regulatory authorities require pharmaceuticals to be sterilized wherever practicable by a
terminal sterilization method that is sterilized in the final container rather than by aseptic …

The spinal cord is unable to regenerate after injury largely due to growth‐inhibition by an
inflammatory response to the injury that fails to resolve, resulting in secondary damage and …

Although contact lenses are promising platforms for ocular drug delivery and have been
extensively studied for that purpose, the influence of sterilization methods on these systems …

Objectives The aim of this work was to study the effect of the physically adsorbed Poloxamer
188 coating polymer on the cytotoxic activity of allicin-loaded gelatin nanoparticles. Methods …