Microwave-assisted synthesis of bioactive six-membered heterocycles and their fused analogues

M Driowya, A Saber, H Marzag, L Demange… - Molecules, 2016 - mdpi.com
This review describes the formation of six-membered heterocyclic compounds and their
fused analogues under microwave activation using modern organic transformations …

[PDF][PDF] Trisubstituted imidazole synthesis: A review

N Rani, A Sharma, R Singh - Mini-Review. Org. Chem, 2015 - researchgate.net
Imidazole, an important azole heterocycle, having biological and medicinal properties
prompted various research groups to develop different synthetic routes to this heterocycle …

Microwave assisted synthesis of imidazoles-A review

G Kumar Gupta, N Rani, V Kumar - Mini-Reviews in Organic …, 2012 - ingentaconnect.com
Imidazoles comprise a major class of five-membered heterocyclic compounds and have
been found to be an integral part of many significant pharmacological active compounds in …

Europium Triflate–Catalyzed One‐Pot Synthesis of 2,4,5‐Trisubstituted‐1H‐imidazoles via a Three‐component Condensation

C Yu, M Lei, W Su, Y Xie - Synthetic Communications, 2007 - Taylor & Francis
A simple, efficient, and practical procedure for synthesis of 2, 4, 5‐trisubstituted‐1 H‐
imidazoles via the condensation of benzoin or acetoin, aromatic aldehydes, and ammonium …

Molecular docking evaluation of imidazole analogues as potent Candida albicans 14α-demethylase inhibitors

N Rani, P Kumar, R Singh… - Current Computer-Aided …, 2015 - ingentaconnect.com
Candida albicans is one of the most important causes of life-threating fungal infections.
Lanosterol 14α-demethylase (Cytochrome P450DM) is the target enzyme of azole antifungal …

Amberlyst A-15: Reusable catalyst for the synthesis of 2,4,5-trisubstituted and 1,2,4,5-tetrasubstituted-1H-imidazoles under MW irradiation

SS Pandit, SK Bhalerao, US Aher, GL Adhav… - Journal of Chemical …, 2011 - Springer
One-pot multi-component condensation of benzyl, aldehydes, ammonium acetate and
primary amines were used for synthesis of 2, 4, 5-trisubstituted and 1, 2, 4, 5-tetrasubstituted …

Phenylethyl-substituted pyrimido [2, 1-f] purinediones and related compounds: structure–activity relationships as adenosine A1 and A2A receptor ligands

A Drabczyńska, CE Müller, A Schiedel… - Bioorganic & medicinal …, 2007 - Elsevier
The synthesis of N-(un) substituted-phenylalkylpyrimido [2, 1-f] purinediones was performed
starting with 7-(3-chloropropyl)-8-bromotheophylline and 7-(3-chloropropyl)-8-bromo-1, 3 …

Synthesis and antibacterial evaluation of diaminomaleonitrile-based azo-Schiff bases and 8,9-dihydro-7H-purine-6-carboxamides

A Sheykhi-Estalkhjani, NO Mahmoodi… - Research on Chemical …, 2020 - Springer
Some new DAMN-based Schiff base 6a–6g were synthesized via a condensation reaction of
the corresponding azo dyes with 1-(2-amino-1, 2-dicyanovinyl)-3-phenylurea. In …

β-Enamino Esters in Heterocyclic Synthesis: Synthesis of Pyrazolone and Pyridinone Derivatives

AM Salaheldin, MA Al-Sheikh - Molecules, 2010 - mdpi.com
Molecules | Free Full-Text | β-Enamino Esters in Heterocyclic Synthesis: Synthesis of
Pyrazolone and Pyridinone Derivatives Next Article in Journal MALDI-TOF MS Analysis of …

Reaction of 2, 3-diaminomaleonitrile with diones

Y Kubota, T Shibata, E Babamoto-Horiguchi, J Uehara… - Tetrahedron, 2009 - Elsevier
2, 3-Diaminomaleonitrile (DAMN) was allowed to react with 2, 6-heptanedione to produce
(2Z)-2-amino-3-[(1E)-3-methylcyclohex-2-enylideneamino] but-2-enedinitrile and (2Z)-2 …