Using genetics for social science

KP Harden, PD Koellinger - Nature human behaviour, 2020 - nature.com
Social science genetics is concerned with understanding whether, how and why genetic
differences between human beings are linked to differences in behaviours and …

Advanced paternal age effects in neurodevelopmental disorders—review of potential underlying mechanisms

M Janecka, J Mill, MA Basson, A Goriely… - Translational …, 2017 - nature.com
Multiple epidemiological studies suggest a relationship between advanced paternal age
(APA) at conception and adverse neurodevelopmental outcomes in offspring, particularly …

Estimation of genetic correlation via linkage disequilibrium score regression and genomic restricted maximum likelihood

G Ni, G Moser, S Ripke, BM Neale, A Corvin… - The American Journal of …, 2018 - cell.com
Genetic correlation is a key population parameter that describes the shared genetic
architecture of complex traits and diseases. It can be estimated by current state-of-art …

Genome-wide analysis identifies 12 loci influencing human reproductive behavior

N Barban, R Jansen, R De Vlaming, A Vaez… - Nature …, 2016 - nature.com
The genetic architecture of human reproductive behavior—age at first birth (AFB) and
number of children ever born (NEB)—has a strong relationship with fitness, human …

Hidden heritability due to heterogeneity across seven populations

FC Tropf, SH Lee, RM Verweij, G Stulp… - Nature human …, 2017 - nature.com
Meta-analyses of genome-wide association studies, which dominate genetic discovery, are
based on data from diverse historical time periods and populations. Genetic scores derived …

Paternal age and psychiatric disorders: A review

H de Kluiver, JE Buizer‐Voskamp… - American Journal of …, 2017 - Wiley Online Library
We review the hypotheses concerning the association between the paternal age at
childbearing and childhood psychiatric disorders (autism spectrum‐and attention …

Risk of psychiatric illness from advanced paternal age is not predominantly from de novo mutations

J Gratten, NR Wray, WJ Peyrot, JJ McGrath… - Nature …, 2016 - nature.com
The offspring of older fathers have higher risk of psychiatric disorders such as schizophrenia
and autism. Paternal-age-related de novo mutations are widely assumed to be the …

Paternal-age-related de novo mutations and risk for five disorders

JL Taylor, JCPG Debost, SU Morton, EM Wigdor… - Nature …, 2019 - nature.com
There are established associations between advanced paternal age and offspring risk for
psychiatric and developmental disorders. These are commonly attributed to genetic …

The role of genetic liability in the association of urbanicity at birth and during upbringing with schizophrenia in Denmark

D Paksarian, BB Trabjerg, KR Merikangas… - Psychological …, 2018 - cambridge.org
BackgroundStudies have indicated that the association of urbanicity at birth and during
upbringing with schizophrenia may be driven by familial factors such as genetic liability. We …

Advanced paternal age and risk of schizophrenia in offspring–review of epidemiological findings and potential mechanisms

V Khachadourian, N Zaks, E Lin, A Reichenberg… - Schizophrenia …, 2021 - Elsevier
A large number of studies have examined the association between advanced paternal age
(APA) and risk of schizophrenia in offspring. Here we present an overview of …