Evidence for central sensitization in patients with osteoarthritis pain: a systematic literature review

E Lluch, R Torres, J Nijs… - European journal of …, 2014 - Wiley Online Library
Hyperexcitability of the central nervous system (CNS) has been suggested to play an
important role in the chronic pain experienced by osteoarthritis (OA) patients. A systematic …

[HTML][HTML] Quantitative sensory testing in painful osteoarthritis: a systematic review and meta-analysis

AK Suokas, DA Walsh, DF McWilliams, L Condon… - Osteoarthritis and …, 2012 - Elsevier
OBJECTIVE: To systematically review the use of Quantitative sensory testing (QST) in pain
characterisation (phenotyping) in Osteoarthritis (OA). METHODS: Six bibliographic …

Psychophysical and functional imaging evidence supporting the presence of central sensitization in a cohort of osteoarthritis patients

SE Gwilym, JR Keltner, CE Warnaby… - Arthritis Care & …, 2009 - Wiley Online Library
Objective The groin pain experienced by patients with hip osteoarthritis (OA) is often
accompanied by areas of referred pain and changes in skin sensitivity. We aimed to identify …

Osteoarthritis pain: nociceptive or neuropathic?

M Thakur, AH Dickenson, R Baron - Nature Reviews Rheumatology, 2014 - nature.com
In this article, we present the case for the existence of a subgroup of patients with
osteoarthritis (OA) who experience pain with neuropathic features. Recognizing these …

[HTML][HTML] Neuropathic pain symptoms in a community knee OA cohort

JR Hochman, L Gagliese, AM Davis… - Osteoarthritis and …, 2011 - Elsevier
Objective A neuropathic pain (NP) questionnaire may facilitate the identification of a
neuropathic component to osteoarthritis (OA) pain. An existing questionnaire, the …

[HTML][HTML] Is tactile acuity altered in people with chronic pain? A systematic review and meta-analysis

MJ Catley, NE O'Connell, C Berryman, FF Ayhan… - The Journal of …, 2014 - Elsevier
Impaired tactile acuity in people with chronic pain conditions has been suggested to reflect
altered cortical representation of the painful body part, and treatments that aim to improve …

High-intensity versus low-level laser therapy in the treatment of patients with knee osteoarthritis: a randomized controlled trial

AR Kheshie, MSM Alayat, MME Ali - Lasers in medical science, 2014 - Springer
The aim of this randomized controlled study was to compare the effects of low-level laser
therapy (LLLT) and high-intensity laser therapy (HILT) on pain relief and functional …

Altered central sensitization and pain modulation in the CNS in chronic joint pain

L Arendt-Nielsen, ST Skou, TA Nielsen… - Current osteoporosis …, 2015 - Springer
Musculoskeletal pain disorders are the second largest contributor to global disability
underlining the significance of effective treatments. However, treating chronic …

Prediction of persistent pain after total knee replacement for osteoarthritis

H Lundblad, A Kreicbergs… - The Journal of Bone & …, 2008 - boneandjoint.org.uk
We suggest that different mechanisms underlie joint pain at rest and on movement in
osteoarthritis and that separate assessment of these two features with a visual analogue …

[PDF][PDF] Pain sensitisation in osteoarthritis

L Arendt-Nielsen - Clin Exp Rheumatol, 2017 - clinexprheumatol.org
Treating chronic musculoskeletal pain, and chronic joint pain (osteoarthritis (OA)) in
particular, is challenging as the peripheral and central pain mechanisms are not fully …