Biological activity of natural and synthetic peptides as anticancer agents

LV Bauso, V La Fauci, S Munaò, D Bonfiglio… - International Journal of …, 2024 - mdpi.com
Cancer is one of the leading causes of morbidity and death worldwide, making it a serious
global health concern. Chemotherapy, radiotherapy, and surgical treatment are the most …

Natural Anticancer Peptides from Marine Animal Species: Evidence from In Vitro Cell Model Systems

M Librizzi, C Martino, M Mauro, G Abruscato, V Arizza… - Cancers, 2023 - mdpi.com
Simple Summary Anticancer peptides are short aminoacidic chains, which display selective
cytotoxicity mostly against tumor, but not healthy, cells through interference with intracellular …

Enhanced efficacy of combined VEGFR peptide–drug conjugate and anti-PD-1 antibody in treating hepatocellular carcinoma

J Liu, Y Bai, X Liu, B Zhou, P Sun, Y Wang, S Ju… - Scientific Reports, 2024 - nature.com
This study aimed to design a VEGFR-targeting peptide–drug conjugate with the ability to
decrease tumor burden and suppress tumor angiogenesis, and to further evaluate the …

Evaluation of anti-cancer effects of carnosine and melittin-loaded niosomes in MCF-7 and MDA-MB-231 breast cancer cells

MMA Hussein, A Abdelfattah-Hassan… - Frontiers in …, 2023 - frontiersin.org
Background: We investigated the anti-cancer effect of carnosine-loaded niosomes (Car-NIO)
and melittin-loaded niosomes (Mel-NIO) with olaparib in breast cancer cell lines (MCF-7 and …

Honey bee venom loaded nanomaterials: A promising avenue for therapeutic delivery

J Aher, V Jadhav, A Bhagare, D Lokhande - Nano-Structures & Nano …, 2024 - Elsevier
Bee venom and nanomaterial are promising new areas of research with the potential to
revolutionize various medical treatments. Because of its potential medicinal uses, bee …

Artificial intelligence and machine learning in clinical pharmacological research

B Mayer, D Kringel, J Lötsch - Expert Review of Clinical …, 2024 - Taylor & Francis
Background Clinical pharmacology research has always involved computational analysis.
With the abundance of drug-related data available, the integration of artificial intelligence …

[HTML][HTML] Recent advances in liposomes and peptide-based therapeutics for glioblastoma treatment

MA Jourdain, J Eyer - Journal of Controlled Release, 2024 - Elsevier
In the context of glioblastoma treatment, the penetration of drugs is drastically limited by the
blood-brain-barrier (BBB). Emerging therapies have focused on the field of therapeutic …

[HTML][HTML] Anticancer peptides from induced tumor-suppressing cells for inhibiting osteosarcoma cells

CP Cui, QJ Huo, X Xiong, KX Li, P Ma… - American Journal of …, 2023 - ncbi.nlm.nih.gov
Osteosarcoma (OS) is the most frequent primary bone cancer, which is mainly suffered by
children and young adults. While the current surgical treatment combined with …

Anticancer activities of natural antimicrobial peptides from animals

B Qu, J Yuan, X Liu, S Zhang, X Ma, L Lu - Frontiers in Microbiology, 2024 - frontiersin.org
Cancer is the most common cause of human death worldwide, posing a serious threat to
human health and having a negative impact on the economy. In the past few decades …

Cytotoxic Effects of Plant Secondary Metabolites and Naturally Occurring Bioactive Peptides on Breast Cancer Model Systems: Molecular Mechanisms

D Zasheva, P Mladenov, S Zapryanova… - Molecules, 2024 - mdpi.com
Breast cancer is the second leading cause of death among women, and the number of
mortal cases in diagnosed patients is constantly increasing. The search for new plant …