BACKGROUND The LH surge induces great physiological changes within the preovulatory
follicle, which culminate in the ovulation of a mature oocyte that is capable of supporting …

The human mitochondrial genome is extremely small compared with the nuclear genome,
and mitochondrial genetics presents unique clinical and experimental challenges. Despite …

BACKGROUND Polycystic ovary syndrome (PCOS) is a common metabolic dysfunction and
heterogeneous endocrine disorder in women of reproductive age. Although patients with …

The epidermal growth factor receptor (EGFR) is the prototypical member of a family of
membrane-associated intrinsic tyrosine kinase receptors, the ErbB family. EGFR is activated …

Before ovulation in mammals, a cascade of events resembling an inflammatory and/or tissue
remodeling process is triggered by luteinizing hormone (LH) in the ovarian follicle. Many LH …

Successful ovulation requires that developmentally competent oocytes are released with
appropriate timing from the ovarian follicle. Somatic cells of the follicle sense the ovulatory …

There has been an improvement in the blastocyst rates achieved following in-vitro embryo
production that can largely be attributed to improved embryo culture conditions based on an …

The first edition of the Textbook of Assisted Reproductive Techniques was published in
2001. As the textbook now enters its sixth edition, some 45 years since the birth of Louise …

The ovarian follicle luteinizing hormone (LH) signaling molecules that regulate oocyte
meiotic maturation have recently been identified. The LH signal reduces preovulatory follicle …

Cytokines are key regulators of ovarian physiology, particularly in relation to folliculogenesis
and ovulation, where they contribute to creating an environment supporting follicle selection …