The role of the adenosine system in epilepsy and its comorbidities

JA Baltos, PM Casillas‐Espinosa… - British Journal of …, 2024 - Wiley Online Library
Epilepsy is one of the most serious and common chronic neurological conditions,
characterised by recurrent hypersynchronous electrical activity in the brain that lead to …

Roles of aging in sleep

HH Zhong, BO Yu, D Luo, LY Yang, J Zhang… - Neuroscience & …, 2019 - Elsevier
With aging, various factors deteriorate the normal sleep process that is essential for the
restoration of functional and physical performance. Due to aging-related diseases, life …

Inhibiting the microglia activation improves the spatial memory and adult neurogenesis in rat hippocampus during 48 h of sleep deprivation

M Wadhwa, A Prabhakar, K Ray, K Roy… - Journal of …, 2017 - Springer
Background Sleep deprivation (SD) leads to cognitive impairment. Neuroinflammation could
be a significant contributing factor in the same. An increase in regional brain pro …

Caffeine and modafinil ameliorate the neuroinflammation and anxious behavior in rats during sleep deprivation by inhibiting the microglia activation

M Wadhwa, G Chauhan, K Roy, S Sahu… - Frontiers in Cellular …, 2018 - frontiersin.org
Background: Sleep deprivation (SD) plagues modern society due to the professional
demands. It prevails in patients with mood and neuroinflammatory disorders. Although …

[HTML][HTML] A brief period of sleep deprivation causes spine loss in the dentate gyrus of mice

F Raven, P Meerlo, EA Van der Zee, T Abel… - … of Learning and …, 2019 - Elsevier
Sleep and sleep loss have a profound impact on hippocampal function, leading to memory
impairments. Modifications in the strength of synaptic connections directly influences …

Sleep deprivation induces spatial memory impairment by altered hippocampus neuroinflammatory responses and glial cells activation in rats

M Wadhwa, P Kumari, G Chauhan, K Roy… - Journal of …, 2017 - Elsevier
We aimed to investigate the glial cells activation as a potential mechanism involved in the
sleep deprivation (SD) induced cognitive impairment through changes in inflammatory …

Intricate role of sleep deprivation in modulating depression: focusing on BDNF, VEGF, serotonin, cortisol, and TNF-α

S Vaseghi, A Mostafavijabbari, MS Alizadeh… - Metabolic Brain …, 2023 - Springer
In this review article, we aimed to discuss intricate roles of SD in modulating depression in
preclinical and clinical studies. Decades of research have shown the inconsistent effects of …

Heat stress induced oxidative damage and perturbation in BDNF/ERK1/2/CREB axis in hippocampus impairs spatial memory

NR Chauhan, R Kumar, A Gupta, RC Meena… - Behavioural Brain …, 2021 - Elsevier
Heat exposure is an environmental stress that causes diverse heat related
pathophysiological changes under extreme conditions. The brain including hippocampal …

Summary of drug therapy to treat cognitive impairment-induced obstructive sleep apnea

D He, J Chen, X Du, L Xu - Frontiers in Cellular Neuroscience, 2023 - frontiersin.org
Obstructive sleep apnea (OSA) is a severe sleep disorder associated with intermittent
hypoxia and sleep fragmentation. Cognitive impairment is a signifi-cant and common OSA …

Caffeine Improve Memory and Cognition via Modulating Neural Progenitor Cell Survival and Decreasing Oxidative Stress in Alzheimer's Rat Model

V Tiwari, A Mishra, S Singh… - Current Alzheimer …, 2023 - ingentaconnect.com
Aims: Caffeine possesses potent antioxidant, anti-inflammatory and anti-apoptotic activities
against a variety of neurodegenerative diseases, including Alzheimer's disease (AD) and …