The potential role of optical biopsy in the study and diagnosis of environmental enteric dysfunction

AJ Thompson, M Hughes, S Anastasova… - Nature Reviews …, 2017 - nature.com
Environmental enteric dysfunction (EED) is a disease of the small intestine affecting children
and adults in low and middle income countries. Arising as a consequence of repeated …

Endomicroscopy for computer and robot assisted intervention

S Zuo, GZ Yang - IEEE Reviews in Biomedical Engineering, 2017 - ieeexplore.ieee.org
Endomicroscopy is a new technique that allows human tissue to be characterized in vivo
and in situ, circumventing the need for conventional biopsy and histology. Despite increased …

Fiber bundle endocytoscopy

M Hughes, TP Chang, GZ Yang - Biomedical optics express, 2013 - opg.optica.org
Endocytoscopy is an optical biopsy technique which uses a miniaturized camera to capture
white light microscopy images through an endoscope. We have developed an alternative …

Line-scanning fiber bundle endomicroscopy with a virtual detector slit

M Hughes, GZ Yang - Biomedical optics express, 2016 - opg.optica.org
Coherent fiber bundles can be used to relay the image plane from the distal tip of an
endomicroscope to an external confocal microscopy system. The frame rate is therefore …

Low-cost high-resolution microendoscopy for the detection of esophageal squamous cell neoplasia: an international trial

MA Protano, H Xu, G Wang, AD Polydorides… - Gastroenterology, 2015 - Elsevier
Background & Aims Esophageal squamous cell neoplasia has a high mortality rate as a
result of late detection. In high-risk regions such as China, screening is performed by Lugol's …

Real-timing processing of fiber bundle endomicroscopy images in python using pyfibrebundle

MR Hughes - Applied Optics, 2023 - opg.optica.org
Fiber imaging bundles allow the transfer of optical images from place-to-place along narrow
and flexible conduits. Traditionally used extensively in medical endoscopy, bundles are now …

[HTML][HTML] Selective plane illumination optical endomicroscopy with polymer imaging fibers

P Roldán-Varona, CA Ross, L Rodríguez-Cobo… - APL Photonics, 2023 - pubs.aip.org
Imaging fibers are used to perform real-time fluorescence endomicroscopy, in vivo, in situ,
with the goal of increasing diagnostic information for a plethora of organ systems and …

High speed, line-scanning, fiber bundle fluorescence confocal endomicroscopy for improved mosaicking

M Hughes, GZ Yang - Biomedical optics express, 2015 - opg.optica.org
A significant limitation of fiber bundle endomicroscopy systems is that the field of view tends
to be small, usually only several hundred micrometers in diameter. Image mosaicking …

Scanning darkfield high-resolution microendoscope for label-free microvascular imaging

H Hou, Y Tang, JB Coole, A Kortum… - Biomedical Optics …, 2023 - opg.optica.org
Characterization of microvascular changes during neoplastic progression has the potential
to assist in discriminating precancer and early cancer from benign lesions. Here, we …

High-resolution microendoscopy: a point-of-care diagnostic for cervical dysplasia in low-resource settings

BD Grant, JHTG Fregnani, JCP Resende… - European Journal of …, 2017 - journals.lww.com
Cervical cancer is the third leading cause of cancer-related death among women in low-to-
middle income countries. Pap testing and pathological services are difficult to implement …