Spiro heterocycle frameworks are a class of organic compounds that possesses unique
structural features making them highly sought-after targets in drug discovery due to their …

Heterocycles are a vital class of compounds in numerous fields, including drug discovery,
agriculture, and materials science. Efficient methods for the synthesis of heterocycles remain …

An unprecedented radical-promoted strategy involving a domino alkylation/intramolecular
C5-annulation of N-acryloyl-4-amino coumarin has been devised for the assembly of 4, 5 …

Malignant melanoma is the most invasive skin cancer with the highest risk of death. The
inhibition of BRAFV600E appears relevant for overcoming secondary resistance developed …

Ruthenium (II/III) coordination compounds have gained widespread attention as
chemotherapy drugs, photosensitizers, and photodynamic therapy reagents. Herein, a family …

A series of mono-peptide, di-peptide and tri-peptide derivatives linked to a coumarin scaffold
(5a–c, 7a–c, and 9a–c) were synthesized via the azide-coupling method from corresponding …

Toward the development of effective metal-based coordination drugs for the treatment of
cisplatin-resistant cancers, we report four new ruthenium (II) coordination compounds …

This review provides an overview of the recent advances in the synthesis of diverse
heterocyclic compounds using thiosemicarbazide as a key building block via …

Most of the traditional fluorescent molecules have the advantages of high fluorescence
quantum yield, good stability, and excellent structural adjustability, but they exhibit the …

Coumarins, a group of naturally occurring compounds, have been reported to demonstrate
anticancer potential. These substances, distinguished by their combined benzene and α …